A nurse is preparing to administer medications to a client who has syndrome of inappropriate antidiuretic hormone (SIADH). Which of the following medications should the nurse question?

Choice A reason: Acetone Breath

Acetone breath is typically associated with diabetic ketoacidosis (DKA), not hyperosmolar hyperglycemic syndrome (HHS). In DKA, the body produces high levels of ketones, leading to a fruity or acetone-like breath odor. HHS, on the other hand, does not usually involve significant ketone production, so acetone breath is not a characteristic feature of HHS.

Choice B reason: Fever

Fever can be a clinical manifestation of HHS, often indicating an underlying infection, which is a common precipitating factor for HHS. Infections can exacerbate hyperglycemia and contribute to the development of HHS, making fever a relevant symptom to consider.

Choice C reason: 68 Years of Age

While age itself is not a clinical manifestation, HHS predominantly affects older adults, particularly those with type 2 diabetes. Therefore, being 68 years old is consistent with the typical demographic affected by HHS, but it is not a direct clinical manifestation.

Choice D reason: Serum Glucose 800 mg/dL

A serum glucose level of 800 mg/dL is significantly elevated and is a hallmark of HHS2. Normal serum glucose levels range from 74 to 106 mg/dL. Such high levels of glucose are indicative of severe hyperglycemia, which is a defining characteristic of HHS.

Choice E reason: Serum Bicarbonate 15 mEq/L

A serum bicarbonate level of 15 mEq/L is below the normal range of 21 to 28 mEq/L. This indicates metabolic acidosis, which can occur in HHS due to severe dehydration and impaired renal function. Although metabolic acidosis is more pronounced in DKA, it can still be present in HHS.

Choice F reason: Insidious Onset

HHS typically has an insidious onset, developing slowly over days to weeks. This gradual progression contrasts with the rapid onset of DKA and is a key feature in the clinical presentation of HHS.

The correct answer is a. Insulin is stable at room temperature for one month.

Choice A Reason:

Insulin is stable at room temperature (between 59°F and 86°F) for up to one month. This is important for patients to know, especially if they do not have immediate access to refrigeration. However, it is crucial to avoid exposing insulin to extreme temperatures, such as direct sunlight or freezing conditions, as these can degrade the medication’s effectiveness.

Choice B Reason:

While some types of insulin can be mixed in the same syringe, this practice is not universally applicable to all insulin types. For example, rapid-acting and intermediate-acting insulins can sometimes be mixed, but long-acting insulins should not be mixed with other insulins. Therefore, this statement is not entirely accurate and should be clarified based on the specific types of insulin being used.

Choice C Reason:

Storing insulin in the freezer is not recommended as freezing can damage the insulin, rendering it ineffective. Insulin should be stored in a refrigerator at temperatures between 36°F and 46°F. If insulin is accidentally frozen, it should not be used.

Choice D Reason:

While it is advisable for clients with type 1 diabetes to have backup medication and supplies, storing them in a car is not recommended due to the potential for extreme temperature fluctuations. Insulin and other diabetes supplies should be kept in a stable, controlled environment to ensure their efficacy.