A nurse is preparing to administer topotecan IV to a client.
Which of the following medications should the nurse expect to administer to treat the adverse effects of topotecan?

Granisetron.

Insulin lispro.

Docusate sodium.

Prednisone.

Answer and Explanation

The Correct Answer is A

Choice A rationale

Granisetron is a 5-HT3 receptor antagonist used to treat chemotherapy-induced nausea and vomiting, a common adverse effect of topotecan.

Choice B rationale

Insulin lispro is a rapid-acting insulin used to manage blood glucose levels in diabetic patients, not to treat adverse effects of topotecan.

Choice C rationale

Docusate sodium is a stool softener used to prevent constipation by increasing the water content of stool, unrelated to topotecan's adverse effects.

Choice D rationale

Prednisone is a corticosteroid used to treat inflammation and immune responses, but it is not specifically indicated for the adverse effects of topotecan.

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Correct Answer is C

Explanation

Choice A rationale

Albuterol, a beta-agonist, typically increases heart rate, so bradycardia is not expected. Normal heart rate: 60-100 beats/min.

Choice B rationale

Albuterol is a bronchodilator and should reduce wheezing, not cause it. Its action relaxes bronchial muscles, improving airflow.

Choice C rationale

Albuterol stimulates beta-2 receptors, causing tremors due to increased skeletal muscle activity. This is a common side effect.

Choice D rationale

Albuterol can cause nervousness and tremors rather than inducing sleepiness. It's more likely to stimulate than sedate.

A. Acetaminophen toxicity. B. Gastrointestinal bleed. C. Acute bronchospasm. D. Morphine toxicity.

Correct Answer is A

Explanation

Choice A rationale

Acetylcysteine is the antidote for acetaminophen toxicity. It replenishes glutathione stores and detoxifies N-acetyl-p-benzoquinone imine (NAPQI), a toxic metabolite, preventing liver damage.

Choice B rationale

Acetylcysteine does not have a role in treating gastrointestinal bleeds. Management of gastrointestinal bleeds typically involves hemostatic agents, proton pump inhibitors, and endoscopic interventions.

Choice C rationale

Acute bronchospasm is treated with bronchodilators like albuterol, not acetylcysteine. While acetylcysteine is a mucolytic, it does not address bronchoconstriction or airway inflammation.

Choice D rationale

Morphine toxicity is treated with naloxone, an opioid antagonist. Acetylcysteine has no effect on opioid receptors and cannot reverse the central nervous system and respiratory depression caused by morphine.

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A nurse is preparing to administer topotecan IV to a client.Which of the following medications should the nurse expect to administer to treat the adverse effects of topotecan?

Nursing Test Bank

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A nurse is preparing to administer topotecan IV to a client.
Which of the following medications should the nurse expect to administer to treat the adverse effects of topotecan?