A nurse is preparing to administer topotecan IV to a client.
Which of the following medications should the nurse expect to administer to treat the adverse effects of topotecan?

Choice A rationale

Educating the client on the consequences of not taking valproic acid is important for informed decision-making. Without the medication, seizure control may be compromised, leading to potential health risks.

Choice B rationale

Taking valproic acid with food can help minimize gastrointestinal side effects such as nausea by reducing gastric irritation and improving drug absorption.

Choice C rationale

Documenting the client's refusal in the medication administration record ensures accurate medical records and provides information for future healthcare decisions and assessments.

Choice D rationale

Enteric-coated formulations of valproic acid can reduce gastrointestinal irritation by allowing the drug to pass through the stomach and dissolve in the intestine.

Choice A rationale

Infiltration of the peripheral IV can cause tissue damage and decreased medication efficacy. Immediate intervention is required to prevent complications.

Choice B rationale

Increased blood pressure can be a common effect of dopamine infusion. Monitoring and dose adjustment may be needed, but it is not an immediate threat.

Choice C rationale

Occasional PVCs can occur with dopamine infusion. While monitoring is necessary, they are not immediately life-threatening and may not require urgent intervention.

Choice D rationale

A heart rate of 105/min is a common side effect of dopamine and does not usually necessitate immediate intervention unless accompanied by other symptoms.