A nurse is reinforcing discharge teaching to a client who has a new prescription for sertraline (Zoloft) for posttraumatic stress disorder. Which of the following statements should the nurse include?

A. Orange juice does not interact with simvastatin and does not need to be avoided.

B. Coenzyme Q10 (CoQ10) supplements are sometimes taken by patients on statins to help alleviate the side effects like muscle pain, but they do not need to be avoided.

C. Grapefruit juice should be avoided while taking simvastatin because it contains compounds that interfere with the enzymes that metabolize statins, potentially leading to increased drug levels and greater risk of side effects such as muscle damage.

D. Not all fruit juices interact with simvastatin; the specific concern is with grapefruit juice.

Explanation:

A. Discussing how food can increase the symptoms of depression is not the priority in this situation; the immediate concern is the interaction between phenelzine and wine.

B. Admitting the client to the psychiatric unit is not necessary based solely on the consumption of wine with phenelzine; assessing the client's condition is the priority.

C. Discussing the effects of wine on the action of antidepressants is important, but assessing the client's current status takes precedence.

D. Assessing the client's blood pressure is the priority action because phenelzine is an MAOI, and consuming wine while taking MAOIs can lead to a hypertensive crisis.