A nurse is reinforcing education about the inheritance patterns of fragile X syndrome to a couple who have a family history of the disorder. Which of the following statements should the nurse make?
“Fragile X syndrome follows an autosomal recessive pattern, so both genetic parents must carry the gene mutation for a child to be affected."
"Since your child has fragile X syndrome, all of your future sons will also have the condition, but your daughters will not be affected."
“Fragile X syndrome is inherited in a mitochondrial pattern which means it is passed from the pregnant individual to child through the mitochondrial DNA.”
“Fragile X syndrome is inherited in an X-linked dominant pattern, which means that if a pregnant client carries the gene mutation, each child has a 50% chance of Inheriting the condition."
The Correct Answer is D
A. “Fragile X syndrome follows an autosomal recessive pattern, so both genetic parents must carry the gene mutation for a child to be affected.” Fragile X syndrome is not autosomal recessive; it is X-linked dominant, meaning it is associated with mutations in the FMR1 gene on the X chromosome. Only one copy of the mutated gene is needed to express the condition.
B. "Since your child has fragile X syndrome, all of your future sons will also have the condition, but your daughters will not be affected." This is incorrect because not all sons will necessarily inherit the condition, and daughters can also be affected, though they often have milder symptoms due to having two X chromosomes.
C. “Fragile X syndrome is inherited in a mitochondrial pattern which means it is passed from the pregnant individual to the child through mitochondrial DNA.” Mitochondrial inheritance involves genes from the mother’s mitochondria, but fragile X syndrome is not inherited this way—it is an X-linked disorder passed down through the X chromosome.
D. “Fragile X syndrome is inherited in an X-linked dominant pattern, which means that if a pregnant client carries the gene mutation, each child has a 50% chance of inheriting the condition.” This is correct. Fragile X syndrome is X-linked dominant, and a parent who carries the full mutation has a 50% chance of passing it to each child. Males typically have more severe symptoms than females due to having only one X chromosome.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Allergic rhinitis. Allergic rhinitis is the most common allergic reaction in children, often triggered by environmental allergens such as pollen, dust mites, and pet dander. It presents with symptoms like sneezing, nasal congestion, runny nose, and itchy eyes, affecting a large number of children worldwide.
B. Systemic reaction. Systemic allergic reactions, which affect multiple organ systems, are less common than localized reactions such as allergic rhinitis. They are more severe but do not occur as frequently in children as mild to moderate allergic responses.
C. Hives. Hives (urticaria) are a common allergic skin reaction, often triggered by food, medications, or insect stings. However, while common, they occur less frequently than allergic rhinitis, which is a more persistent condition.
D. Anaphylaxis. Anaphylaxis is a severe and life-threatening allergic reaction, but it is relatively rare compared to allergic rhinitis. It requires immediate medical intervention and is most commonly triggered by food allergies, insect stings, or medications.
Correct Answer is B
Explanation
A. Leukocytes. Leukocytes (white blood cells) are involved in the immune response and are not the primary cells affected in testicular cancer. Cancers of leukocytes include leukemia and lymphoma, not testicular cancer.
B. Germ cells. This is correct. Testicular cancer most commonly arises from germ cells, which are the cells responsible for producing sperm. Germ cell tumors (GCTs) account for over 90% of testicular cancers, including seminomas and non-seminomas.
C. Epithelial cells. Epithelial cells line various tissues and organs, but they are not the primary source of testicular cancer. Epithelial cell cancers, like carcinomas, more commonly affect the skin, lungs, and digestive tract.
D. Lymphocytes. Lymphocytes are a type of white blood cell involved in the immune system. Testicular lymphoma can occur but is rare compared to germ cell tumors, which are the most frequent type of testicular cancer in adolescents and young adults.
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