A nurse is reinforcing teaching about the role of the immune system to a client who has psoriasis. Which of the following explains the immune system dysfunction associated with psoriasis?
Suppression of pro-inflammatory cytokines
Increased production of sebum
Overactivation of T-cells
Decreased number of Langerhans cells in the dermis
The Correct Answer is C
A. Suppression of pro-inflammatory cytokines. Psoriasis is driven by an increase, not suppression, of pro-inflammatory cytokines like TNF-α, IL-17, and IL-23. These cytokines trigger excessive skin cell proliferation and inflammation.
B. Increased production of sebum. Sebum production is linked to conditions like seborrheic dermatitis and acne, not psoriasis. Psoriasis is an autoimmune disorder rather than a condition caused by oil overproduction.
C. Overactivation of T-cells. Psoriasis is an immune-mediated disorder where overactive T-cells attack healthy skin cells, leading to increased inflammation and rapid skin cell turnover. This results in the formation of thick, scaly plaques seen in psoriasis.
D. Decreased number of Langerhans cells in the dermis. Langerhans cells are antigen-presenting cells involved in immune defense. While they may play a role in immune regulation, psoriasis is primarily caused by T-cell hyperactivity rather than a reduction in Langerhans cells.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Cardiac enzymes. Cardiac enzyme tests are used to assess heart damage, such as in myocardial infarction, and are not typically relevant in evaluating a child's nutritional status.
B. Complete blood count. A CBC is a key diagnostic test for assessing nutritional status, as it can reveal anemia (low hemoglobin and hematocrit), infection (elevated white blood cells), and overall health status. It helps identify deficiencies in iron, folate, and vitamin B12, which are common nutritional concerns in children.
C. Blood coagulation tests. Coagulation tests (e.g., PT, INR, aPTT) are used to assess blood clotting disorders and monitor anticoagulant therapy, but they are not standard tests for nutritional assessment unless there is suspicion of a vitamin K deficiency.
D. Arterial blood gases. ABG tests assess respiratory function and acid-base balance, which are more relevant in critically ill patients. They are not routinely used to evaluate a child's nutritional status.
Correct Answer is B
Explanation
A. Prophylactic treatment is offered to those who have been in close contact with an infected child in the past 60 days. While prophylactic antibiotics (such as azithromycin) are recommended for close contacts of an infected person, the timeframe for exposure is within the past 21 days, not 60 days.
B. Severe, prolonged episodes of coughing is a characteristic manifestation of this infection. Pertussis (whooping cough) is marked by severe coughing fits followed by a "whooping" sound during inhalation. The cough is paroxysmal (sudden and violent), prolonged, and can lead to vomiting, exhaustion, or respiratory distress.
C. A painful, stiff neck is a common manifestation of this infection. A stiff neck (nuchal rigidity) is more commonly associated with meningitis, not pertussis. Pertussis primarily affects the respiratory system, causing a severe cough.
D. An antiviral medication is administered to treat this infection. Pertussis is caused by the bacterium Bordetella pertussis, so it is treated with antibiotics (e.g., azithromycin, clarithromycin, or erythromycin), not antivirals.
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