A nurse is reinforcing education to a client who is prescribed clozapine. Which of the following findings should the nurse identify as consistent with agranulocytosis and instruct the client to monitor?

Severe restlessness

Respiratory depression and a comatose state

Sore throat and muscle aches

Increased anxiety and suicidal ideations

Answer and Explanation

The Correct Answer is C

A. Severe restlessness. Severe restlessness, known as akathisia, is a potential side effect of antipsychotic medications but is not indicative of agranulocytosis. Akathisia is associated with excessive movement and an inability to stay still, often requiring dose adjustment or medication to alleviate symptoms.
B. Respiratory depression and a comatose state. Respiratory depression and coma are not linked to agranulocytosis but may occur with overdose or central nervous system depression. Agranulocytosis affects white blood cell levels, leading to increased infection risk rather than sedation or respiratory suppression.
C. Sore throat and muscle aches. Sore throat and muscle aches are early signs of agranulocytosis, a potentially life-threatening condition characterized by a dangerously low neutrophil count. Clients taking clozapine must undergo regular white blood cell monitoring to detect agranulocytosis early and prevent severe infections.
D. Increased anxiety and suicidal ideations. Increased anxiety and suicidal ideations may be related to psychiatric conditions or medication effects but are not specific to agranulocytosis. Clozapine is primarily used for treatment-resistant schizophrenia and may help reduce suicidal behavior rather than induce it.

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Correct Answer is C

Explanation

A. Cyclothymic disorder: Cyclothymic disorder involves chronic mood instability with alternating hypomanic and depressive symptoms for at least two years. These mood fluctuations occur independently of the menstrual cycle and do not meet the criteria for major mood episodes.
B. Postpartum depression: Postpartum depression occurs within weeks to months after childbirth and presents with persistent sadness, fatigue, and emotional distress. It is unrelated to the menstrual cycle and requires medical treatment such as therapy and antidepressants.
C. Premenstrual dysphoric disorder: Premenstrual dysphoric disorder is marked by mood disturbances, including depressed mood, irritability, and anxiety, occurring in the luteal phase before menstruation. Symptoms resolve after menstruation begins, and treatment may include SSRIs, hormonal therapy, or lifestyle modifications.
D. Bipolar disorder: Bipolar disorder involves episodes of mania and depression that are unrelated to hormonal changes in the menstrual cycle. Manic episodes present with impulsivity and grandiosity, while depressive episodes cause low energy and anhedonia, requiring mood stabilizers.

A. "Neurotransmitters are chemical components that allow neurons to store energy for future use." B. "Neurotransmitters are activated by the enzyme transferase." C. "Neurotransmitters function by inhibiting the production of glucose." D. "Neurotransmitters are found throughout the body."

Correct Answer is D

Explanation

A. Neurotransmitters are chemical components that allow neurons to store energy for future use. Neurotransmitters do not store energy; they facilitate communication between neurons by transmitting signals across synapses. Their primary function is to modulate brain activity, not energy storage.
B. Neurotransmitters are activated by the enzyme transferase. Neurotransmitters are not activated by transferase. They are synthesized, stored in vesicles, and released into the synaptic cleft in response to an action potential, where they bind to receptors to elicit a response.
C. Neurotransmitters function by inhibiting the production of glucose. Neurotransmitters do not inhibit glucose production. They play a role in neuronal signaling, affecting mood, cognition, and physiological processes, but do not directly regulate glucose metabolism.
D. Neurotransmitters are found throughout the body. Neurotransmitters exist in both the central and peripheral nervous systems, regulating various functions such as mood, movement, and autonomic responses. They are essential for communication between neurons in the brain and throughout the body.

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A nurse is reinforcing education to a client who is prescribed clozapine. Which of the following findings should the nurse identify as consistent with agranulocytosis and instruct the client to monitor?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is assisting in the care for a client who is exhibiting a depressed mood one week before the start of their menstrual cycle. When collecting data, the nurse should identify that the client is exhibiting manifestations consistent with which of the following disorders?

Correct Answer is C

Explanation

A nurse is reinforcing education to a group of clients about the process of neurotransmission. Which of the following statements about neurotransmission should the nurse make?

Correct Answer is D

Explanation

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