A nurse is reinforcing teaching with the caregivers of an infant who has a prescription for digoxin. Which of the following statements should the nurse make?

A. "He is always hungry.": This is not typically a sign of a congenital heart defect. Many infants are hungry frequently as they grow, so this would not be an alerting sign.

B. "He is fussy for several hours every day.": Fussiness is common in infants and does not necessarily indicate a congenital heart defect.

C. "He tires out during feedings.": This is a concerning sign. Infants with congenital heart defects often have difficulty feeding due to poor oxygenation and energy reserves. Fatigue during feedings is a common symptom of heart defects.

D. "He sleeps all the time.": Sleeping a lot could be normal for a 1-month-old infant, and it would not necessarily indicate a congenital heart defect unless the infant is lethargic or difficult to rouse.

A. Pain: A vaso-occlusive crisis in sickle cell disease occurs when sickled red blood cells block blood flow in small vessels, leading to severe pain, often in the bones, joints, and abdomen. Pain is the hallmark symptom of a vaso-occlusive crisis.

B. Bradycardia: Bradycardia is not typically associated with a vaso-occlusive crisis in sickle cell disease. The child may have an increased heart rate (tachycardia) due to pain, dehydration, or hypoxia.

C. Vomiting: Vomiting is not a direct result of a vaso-occlusive crisis but can occur due to complications such as dehydration or infection.

D. Constipation: Constipation is not a common symptom of a vaso-occlusive crisis. It may occur as a side effect of medications like opioids, which are often used to manage pain in sickle cell patients.