A nurse is reviewing laboratory data for a client who is taking simvastatin to correct plasma lipid levels. Which of the following findings should the nurse identify as an adverse effect of this therapy?

Elevated alanine aminotransferase (ALT).

Elevated troponin T.

Elevated WBC count.

Elevated thyroid-stimulating hormone (TSH).

Answer and Explanation

The Correct Answer is A

Choice A rationale
Elevated alanine aminotransferase (ALT) is an adverse effect of simvastatin therapy. Statins, including simvastatin, can cause liver damage, which is indicated by elevated liver enzymes such as ALT2.
Choice B rationale
Elevated troponin T is not typically associated with simvastatin therapy. Troponin T is a marker for cardiac muscle damage, not a common adverse effect of statins.
Choice C rationale
Elevated WBC count is not a known adverse effect of simvastatin therapy. An elevated WBC count usually indicates an infection or inflammation.
Choice D rationale
Elevated thyroid-stimulating hormone (TSH) is not associated with simvastatin therapy. TSH levels are related to thyroid function, not the effects of statins.

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Correct Answer is C

Explanation

Choice A rationale
Rifampin is an antibiotic used to treat tuberculosis and other bacterial infections. It does not have a known interaction with St. John’s wort.
Choice B rationale
Furosemide is a diuretic used to treat fluid retention and high blood pressure. It does not have a known interaction with St. John’s wort.
Choice C rationale
Citalopram is a selective serotonin reuptake inhibitor (SSRI) used to treat depression. St. John’s wort can interact with SSRIs like citalopram, potentially leading to serotonin syndrome, a serious condition caused by excessive levels of serotonin in the brain.
Choice D rationale
Allopurinol is used to treat gout and kidney stones. It does not have a known interaction with St. John’s wort.

A. Take this medication with meals. B. Reduce dietary fiber while taking the medication. C. Administer an antacid with the medication. D. Increase fluid intake while taking the medication.

Correct Answer is D

Explanation

Choice A rationale
Sucralfate should be taken on an empty stomach, not with meals, to ensure it coats the ulcer effectively.
Choice B rationale
There is no need to reduce dietary fiber while taking sucralfate. Fiber intake does not interfere with the medication’s effectiveness.
Choice C rationale
Antacids should not be taken within 30 minutes before or after taking sucralfate, as they can interfere with its action.
Choice D rationale
Increasing fluid intake is recommended while taking sucralfate to help prevent constipation, a common side effect of the medication.

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A nurse is reviewing laboratory data for a client who is taking simvastatin to correct plasma lipid levels. Which of the following findings should the nurse identify as an adverse effect of this therapy?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is completing an admission assessment for a client who has been taking St. John’s wort. The nurse should identify that which of the following medications can interact with St. John’s wort?

Correct Answer is C

Explanation

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Correct Answer is D

Explanation

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