A nurse is reviewing laboratory data for a client who is taking simvastatin to correct plasma lipid levels. Which of the following findings should the nurse identify as an adverse effect of this therapy?

Elevated alanine aminotransferase (ALT).

Elevated troponin T.

Elevated WBC count.

Elevated thyroid-stimulating hormone (TSH).

Answer and Explanation

The Correct Answer is A

Choice A rationale
Elevated alanine aminotransferase (ALT) is an adverse effect of simvastatin therapy. Statins, including simvastatin, can cause liver damage, which is indicated by elevated liver enzymes such as ALT2.
Choice B rationale
Elevated troponin T is not typically associated with simvastatin therapy. Troponin T is a marker for cardiac muscle damage, not a common adverse effect of statins.
Choice C rationale
Elevated WBC count is not a known adverse effect of simvastatin therapy. An elevated WBC count usually indicates an infection or inflammation.
Choice D rationale
Elevated thyroid-stimulating hormone (TSH) is not associated with simvastatin therapy. TSH levels are related to thyroid function, not the effects of statins.

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Correct Answer is D

Explanation

Choice A rationale
Asthma is not a contraindication for sumatriptan. Sumatriptan is a selective serotonin receptor agonist used to treat migraines by constricting blood vessels in the brain. It does not have a significant impact on respiratory conditions like asthma.
Choice B rationale
Kidney disease is not a contraindication for sumatriptan. However, caution is advised when using sumatriptan in patients with severe renal impairment due to potential accumulation of the drug and its metabolites.
Choice C rationale
Rheumatoid arthritis is not a contraindication for sumatriptan. Sumatriptan’s mechanism of action does not interfere with the inflammatory processes involved in rheumatoid arthritis.
Choice D rationale
Coronary artery disease (CAD) is a contraindication for sumatriptan. Sumatriptan can cause vasoconstriction of coronary arteries, which can exacerbate CAD and increase the risk of myocardial infarction or other cardiac events.

A. Hyperglycemia. B. Stomatitis. C. Fever. D. Constipation.

Correct Answer is D

Explanation

Choice A rationale
Hyperglycemia is not a common adverse effect of colesevelam. Colesevelam is primarily used to lower cholesterol levels and can also help control blood sugar levels in patients with type 2 diabetes.
Choice B rationale
Stomatitis, or inflammation of the mouth, is not typically associated with colesevelam. This medication works in the intestines and is not absorbed into the bloodstream, so it does not commonly cause systemic side effects.
Choice C rationale
Fever is not a known adverse effect of colesevelam. The medication’s side effects are generally limited to the gastrointestinal system.
Choice D rationale
Constipation is a common adverse effect of colesevelam. This medication binds to bile acids in the intestines, which can lead to gastrointestinal side effects such as constipation.

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A nurse is reviewing laboratory data for a client who is taking simvastatin to correct plasma lipid levels. Which of the following findings should the nurse identify as an adverse effect of this therapy?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is reviewing the health history of a client who experiences migraine headaches and has asked about a prescription for sumatriptan. Which of the following conditions should the nurse identify as a contraindication for taking sumatriptan?

Correct Answer is D

Explanation

A nurse is caring for a client who has hyperlipidemia and a new prescription for colesevelam. The nurse should monitor the client for which of the following manifestations as an adverse effect of colesevelam?

Correct Answer is D

Explanation

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