A nurse is reviewing the laboratory data of a client who is receiving filgrastim. Which of the following laboratory values should the nurse monitor to evaluate the effectiveness of the treatment?
INR
BUN
WBC count
Potassium level
The Correct Answer is C
Choice A Reason:
INR (International Normalized Ratio) is incorrect. INR is a measurement used to monitor the effects of anticoagulants like warfarin. It assesses the blood's ability to clot. Filgrastim does not directly affect INR levels, so monitoring INR would not provide information about the effectiveness of filgrastim in stimulating white blood cell production.
Choice B Reason:
BUN (Blood Urea Nitrogen) is incorrect. BUN levels primarily indicate kidney function and hydration status. They are not directly influenced by filgrastim treatment. Monitoring BUN is essential for assessing kidney function but does not reflect the effectiveness of filgrastim therapy in increasing white blood cell counts.
Choice C Reason:
WBC count is correct. Filgrastim is a medication that stimulates the production of white blood cells (WBCs), particularly neutrophils. Therefore, the key laboratory value to monitor for assessing the effectiveness of filgrastim therapy is the WBC count. An increase in the WBC count, particularly in the neutrophil count, signifies the intended therapeutic effect of filgrastim in boosting the immune system's response by increasing the production of these infection-fighting cells.
Choice D Reason:
Potassium level is incorrect. Potassium levels are crucial for heart and muscle function. While certain medications might affect potassium levels, filgrastim's primary action is on stimulating white blood cell production and does not directly impact potassium levels. Monitoring potassium levels is essential for overall health but does not specifically indicate the effectiveness of filgrastim treatment.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A Reason:
Furosemide is not correct. Furosemide is a diuretic used to treat conditions like heart failure and edema by increasing urine output. It is not a contraindication for sildenafil. However, it's essential to monitor blood pressure when these medications are used together, as both can potentially lower blood pressure.
Choice B Reason:
Albuterol is not correct. Albuterol is a bronchodilator commonly used to treat asthma and other respiratory conditions. It doesn't have direct contraindications with sildenafil for erectile dysfunction. Although both medications can cause some cardiovascular effects, they are not typically considered contraindications for each other.
Choice C Reason:
Indomethacin is not correct. Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce inflammation and pain. While it can have effects on blood pressure and the cardiovascular system, it is not a direct contraindication for sildenafil specifically for erectile dysfunction.
Choice D Reason:
Nitroglycerin is correct. Nitroglycerin is a contraindication for sildenafil. Both medications can cause a significant drop in blood pressure. When taken together, they can potentiate each other's effects, leading to a severe decrease in blood pressure, which can be dangerous and potentially life-threatening. Therefore, individuals using nitroglycerin or any nitrate medications should not take sildenafil or other medications for erectile dysfunction due to the risk of hypotension (dangerously low blood pressure).
Correct Answer is D
Explanation
Choice A Reason:
Discard the medication if it is yellow is incorrect. While amphotericin B lipid complex can have a yellowish color, it's important to follow specific guidelines provided by the manufacturer or pharmacy regarding any discoloration or changes in the medication's appearance. Discoloration could indicate degradation or contamination, and it's crucial to adhere to specific institutional policies in such cases.
Choice B Reason:
Administer the medication over 2 hr is incorrect. Amphotericin B lipid complex is usually given over a longer duration (e.g., several hours) due to the potential for infusion-related reactions. Intermittent IV bolus administration over 2 hours might not be appropriate and can increase the risk of adverse reactions.
Choice C Reason:
Use a gravity flow set is incorrect. For medications like amphotericin B lipid complex, which often require precise infusion rates and careful monitoring, using an IV infusion pump is usually recommended instead of a gravity flow set. An infusion pump allows for more accurate control of the infusion rate and reduces the risk of errors.
Choice D Reason:
Prime the tubing with 0.9% sodium chloride is correct. Amphotericin B lipid complex should be administered according to specific instructions and precautions. Priming the IV tubing with 0.9% sodium chloride helps ensure that the medication is effectively delivered to the patient and that the medication is not affected by remnants of previous IV solutions in the tubing.
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