A nurse is reviewing the laboratory results of a client with HELLP syndrome.
Which of the following findings would indicate hemolysis?
Elevated serum creatinine
Elevated serum lactate dehydrogenase (LDH)
Elevated serum alkaline phosphatase (ALP)
Elevated serum uric acid
The Correct Answer is B
Elevated serum lactate dehydrogenase (LDH) indicates hemolysis, which is one of the components of HELLP syndrome. Hemolysis is the destruction of red blood cells that occurs when they pass through damaged blood vessels.
Choice A is wrong because elevated serum creatinine indicates kidney dysfunction, which is not specific for hemolysis.
Choice C is wrong because elevated serum alkaline phosphatase (ALP) indicates liver damage, which is another component of HELLP syndrome, but not specific for hemolysis.
Choice D is wrong because elevated serum uric acid indicates increased purine metabolism, which can be associated with preeclampsia and HELLP syndrome, but not specific for hemolysis.
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Correct Answer is B
Explanation
Elevated serum lactate dehydrogenase (LDH) indicates hemolysis, which is one of the components of HELLP syndrome.Hemolysis is the destruction of red blood cells that occurs when they pass through damaged blood vessels.
Choice A is wrong because elevated serum creatinine indicates kidney dysfunction, which is not specific for hemolysis.
Choice C is wrong because elevated serum alkaline phosphatase (ALP) indicates liver damage, which is another component of HELLP syndrome, but not specific for hemolysis.
Choice D is wrong because elevated serum uric acid indicates increased purine metabolism, which can be associated with preeclampsia and HELLP syndrome, but not specific for hemolysis.
Correct Answer is D
Explanation
Protein excretion of 450 mg indicates proteinuria.Proteinuria is the presence of excess protein in the urine, which can be a sign of kidney damage or disease.Normal protein excretion in a 24-hour urine collection is less than 150 mg.
Choice A is wrong because protein excretion of 150 mg is within the normal range.
Choice B is wrong because protein excretion of 250 mg is slightly above the normal range, but not enough to indicate proteinuria.
Choice C is wrong because protein excretion of 350 mg is also above the normal range, but not enough to indicate proteinuria.
Preeclampsia is a condition that affects some pregnant women, usually after 20 weeks of pregnancy.It causes high blood pressure and proteinuria, which can harm both the mother and the baby.A 24-hour urine collection is a simple lab test that measures what’s in the urine and checks kidney function.The test is done by collecting all the urine passed in a 24-hour period in a special container that must be kept cool until returned to the lab.
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