A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Septic shock is a state of reduced intravascular volume due to extravasation of plasma. It is caused by systemic infections that lead to inflammation and increased leakage in blood vessels. It presents with hypotension, and persistent hypotension indicates that the infusion rate is not addressing the shock status.
A, C, D- These are adverse effects that can be observed with dopamine and could be worsened by increasing the infusion rate.
Correct Answer is A
Explanation
The air bubble should not be expelled from the syringe or aspirate. The air bubble in the syringe of enoxaparin is intended to remain to ensure the full dose of medication is administered.
B-Avoid rubbing a sit may increase the risk of bleeding /irritation
C-The injection is made into the anterolateral or posterolateral aspect of the thigh
D-The skin should not be released before injection as the medication may be injected into the muscle
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