A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
Nursing Test Bank
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Related Questions
Correct Answer is A
Explanation
Carbamazepine is an antiepileptic medication commonly used to treat seizures. One of the potential adverse effects of carbamazepine is blurred vision. This occurs because carbamazepine can affect the function of the eyes, leading to changes in vision. Clients taking carbamazepine should be advised to report any changes in vision, such as blurriness or difficulty focusing, to their healthcare provider promptly.
B,C,D- are not related to carbamazepine use
Correct Answer is D
Explanation
metoclopramide is a dopamine antagonist which could interact with central dopamine receptors to cause tardive dyskinesia. The nurse should monitor the client for tardive dyskinesia, a serious movement disorder that can be caused by high-dose metoclopramide. When administering injections, it is generally recommended to inject the medication into the lateral thigh.
A-ACEIS, ARBS cause angioedema and persistent dry cough
B-Corticosteroids or other immunosuppressants increases risk of fungal infections such as oral candidiasis
C-anticoagulants can cause black stools which is a sign of upper GI bleeding.
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