A nurse is reviewing the list of current medications for a client who has a new prescription for nitroglycerin. The nurse should identify that which of the following client medications is contraindicated for use with nitroglycerin?
Sildenafil
Gemfibrozil
Lansoprazole
Diazepam
The Correct Answer is A
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Diazepam is a benzodiazepine with potential for respiratory depression. It is, therefore, important for the nurse to cautiously monitor the respiratory rate and respond appropriately at each review.
A-Diazepam is an anticonvulsant
B, D- Diazepam has no effect on bowel habits and urinary output
Correct Answer is C
Explanation
Incident reports are documented for incidences that are likely to cause adverse outcomes for the clients or healthcare professionals and, therefore, their occurrence needs to be mitigated. In this case, wrong timing for medications such as insulin may lead to overdose with subsequent hypoglycemia which is detrimental
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