A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?
Excretion
Absorption
Distribution
Metabolism
The Correct Answer is D
A. Excretion is the removal of the drug from the body, typically through the kidneys, and is not related to changes in the drug's potency or solubility.
B. Absorption is the process of the drug entering the bloodstream, not a process that alters the drug's chemical form.
C. Distribution is the process by which the drug is spread throughout the body’s tissues and organs, not
the phase where the drug is altered.
D. Metabolism, primarily occurring in the liver, involves the conversion of drugs into more water-soluble forms, which can either increase or decrease their potency.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Furosemide (Lasix): Furosemide is a diuretic and is not used for motion sickness.
B. Metformin (Glucophage): Metformin is used for diabetes management, not for motion sickness.
C. Naloxone (Narcan): Naloxone is used to reverse opioid overdose, not for motion sickness.
D. Scopolamine (Scopace): Scopolamine is an anticholinergic medication that is commonly used to prevent and treat motion sickness.
Correct Answer is ["A","B"]
Explanation
A. BUN is a waste product of protein metabolism that is excreted by the kidneys. Elevated BUN levels can indicate impaired kidney function or kidney dysfunction. Since kidney dysfunction can affect the elimination of waste products, monitoring BUN is essential to assess the kidney's ability to filter and excrete waste.
B. Creatinine is a waste product of muscle metabolism that is filtered out by the kidneys. It is one of the most reliable indicators of kidney function. When kidney function is impaired, creatinine levels rise in the blood because the kidneys are unable to excrete it efficiently.
C. Lipid panel: This is unrelated to the metabolism of medications.
D. Blood glucose: Blood glucose levels are important for diabetes management but are not directly impacted by kidney dysfunction in relation to medication response.
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