A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?
Excretion
Absorption
Distribution
Metabolism
The Correct Answer is D
A. Excretion is the removal of the drug from the body, typically through the kidneys, and is not related to changes in the drug's potency or solubility.
B. Absorption is the process of the drug entering the bloodstream, not a process that alters the drug's chemical form.
C. Distribution is the process by which the drug is spread throughout the body’s tissues and organs, not
the phase where the drug is altered.
D. Metabolism, primarily occurring in the liver, involves the conversion of drugs into more water-soluble forms, which can either increase or decrease their potency.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Digoxin: This medication is used for heart failure and atrial fibrillation, not for constipation.
B. Sildenafil: This medication is used to treat erectile dysfunction, not constipation.
C. Lactulose: Lactulose is an osmotic laxative commonly used to treat constipation. It works by drawing water into the stool to make bowel movements easier.
D. Spironolactone: Spironolactone is a potassium-sparing diuretic used to treat heart failure and fluid retention, not constipation.
Correct Answer is B
Explanation
A. This is not the correct action because the issue with misoprostol in pregnancy is not related to the route of administration, but rather its potential to cause uterine contractions and harm to the pregnancy. The nurse should not administer the medication at all, regardless of the route, and should notify the physician for further clarification.
B. Misoprostol is contraindicated in pregnancy because it can cause uterine contractions, which may result in a miscarriage or preterm labor. The nurse should not administer this medication and must inform the healthcare provider to reconsider the prescription or explore alternative options to prevent stomach ulcers in pregnant clients.
C. Administering misoprostol to a pregnant client is dangerous, as it can stimulate uterine contractions and threaten the pregnancy. Monitoring for adverse reactions would not be an appropriate course of action, as the medication should not be given to begin with.
D. Even though verifying the patient's identity is always an important step, the main concern here is that misoprostol is contraindicated during pregnancy. The nurse should not administer this medication and must first clarify with the healthcare provider if it is suitable for the pregnant patient.
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