A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?

Excretion

Absorption

Distribution

Metabolism

Answer and Explanation

The Correct Answer is D

A.   Excretion is the removal of the drug from the body, typically through the kidneys, and is not related to changes in the drug's potency or solubility.
B.   Absorption is the process of the drug entering the bloodstream, not a process that alters the drug's chemical form.
C.   Distribution is the process by which the drug is spread throughout the body’s tissues and organs, not
the phase where the drug is altered.
D.   Metabolism, primarily occurring in the liver, involves the conversion of drugs into more water-soluble forms, which can either increase or decrease their potency.

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Correct Answer is B

Explanation

A. Levothyroxine is used to treat hypothyroidism, not hyperglycemia.
B. Levothyroxine is a synthetic thyroid hormone used to treat hypothyroidism, a condition where the thyroid does not produce enough thyroid hormone.
C. Levothyroxine is not used to treat hypokalemia. Hypokalemia would require potassium supplementation or treatment of the underlying cause.
D. Levothyroxine is not used for the treatment of hypoglycemia.

A. Prolonged QT interval B. Spasms of the neck and face C. Nausea D. Vomiting

Correct Answer is A

Explanation

A. Ondansetron (Zofran) can cause a prolonged QT interval, which may lead to arrhythmias. This is a known side effect and should be monitored.
B. Spasms of the neck and face are more likely to occur with medications that have extrapyramidal side effects, such as certain antipsychotics, not ondansetron.
C. Nausea and D. Vomiting are the symptoms ondansetron is intended to treat, so these are not complications.

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A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

You are caring for a new client that got admitted to the unit for abdominal pain. The client takes levothyroxine (Synthroid) at home. The nurse understands that the client is taking levothyroxine (Synthroid) to treat which of the following conditions?

Correct Answer is B

Explanation

A nurse administered ondansetron (Zofran) IV to a client 30 minutes ago. Which of the following findings should the nurse recognize as a complication of this medication?

Correct Answer is A

Explanation

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