A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?
Excretion
Absorption
Distribution
Metabolism
The Correct Answer is D
A. Excretion is the removal of the drug from the body, typically through the kidneys, and is not related to changes in the drug's potency or solubility.
B. Absorption is the process of the drug entering the bloodstream, not a process that alters the drug's chemical form.
C. Distribution is the process by which the drug is spread throughout the body’s tissues and organs, not
the phase where the drug is altered.
D. Metabolism, primarily occurring in the liver, involves the conversion of drugs into more water-soluble forms, which can either increase or decrease their potency.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. A blood potassium level of 3.9 mEq/L is normal and does not require intervention.
B. Urine output of 500 mL in 5 hours is not concerning and is within the expected range.
C. A blood potassium level of 8 mEq/L is dangerously high, indicating hyperkalemia, which can lead to life-threatening arrhythmias.
D. Urine output of 200 mL in 4 hours could be a concern for dehydration or renal issues, but it is not directly related to spironolactone use.
Correct Answer is C
Explanation
A. An allergic reaction: An allergic reaction is an immune response, not the reduction of drug effect.
B. A synergistic effect: A synergistic effect occurs when two drugs enhance each other's effects.
C. An antagonistic effect: An antagonistic effect occurs when one drug reduces or counteracts the effect of another drug.
D. None of the above: The correct term is "antagonistic effect."
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