A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?
Excretion
Absorption
Distribution
Metabolism
The Correct Answer is D
A. Excretion is the removal of the drug from the body, typically through the kidneys, and is not related to changes in the drug's potency or solubility.
B. Absorption is the process of the drug entering the bloodstream, not a process that alters the drug's chemical form.
C. Distribution is the process by which the drug is spread throughout the body’s tissues and organs, not
the phase where the drug is altered.
D. Metabolism, primarily occurring in the liver, involves the conversion of drugs into more water-soluble forms, which can either increase or decrease their potency.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Ondansetron (Zofran) can cause a prolonged QT interval, which may lead to arrhythmias. This is a known side effect and should be monitored.
B. Spasms of the neck and face are more likely to occur with medications that have extrapyramidal side effects, such as certain antipsychotics, not ondansetron.
C. Nausea and D. Vomiting are the symptoms ondansetron is intended to treat, so these are not complications.
Correct Answer is B
Explanation
A. Duration of action refers to the length of time the medication has an effect, not how it moves through the body.
B. Absorption is the process by which a drug moves from the site of administration into the bloodstream or circulating fluids.
C. Diffusion is part of absorption, but absorption is the broader term that encompasses all mechanisms by which the drug enters the bloodstream.
D. Onset of action refers to the time it takes for the medication to begin working, not the movement of the drug through the body.
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