A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?
Excretion
Absorption
Distribution
Metabolism
The Correct Answer is D
A. Excretion is the removal of the drug from the body, typically through the kidneys, and is not related to changes in the drug's potency or solubility.
B. Absorption is the process of the drug entering the bloodstream, not a process that alters the drug's chemical form.
C. Distribution is the process by which the drug is spread throughout the body’s tissues and organs, not
the phase where the drug is altered.
D. Metabolism, primarily occurring in the liver, involves the conversion of drugs into more water-soluble forms, which can either increase or decrease their potency.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Mannitol is an osmotic diuretic, and although it can cause dehydration and electrolyte imbalances, it does not specifically cause hypokalemia as a primary side effect.
B. Spironolactone is a potassium-sparing diuretic, so it is less likely to cause hypokalemia. In fact, it can cause hyperkalemia.
C. Furosemide is a loop diuretic that increases urine output and can lead to potassium loss, causing hypokalemia. This is a common complication of loop diuretics.
D. Metformin is an oral antidiabetic medication and is not a diuretic, so it is not associated with hypokalemia.
Correct Answer is C
Explanation
A. Pinpoint pupils, coma, and respiratory depression: These are signs of opioid overdose, not abstinence syndrome.
B. Sedation, fixed pupils, and nausea: This may be associated with opioid overdose, not withdrawal.
C. Fever, hypertension, vomiting, anxiety, and abdominal cramping: These are classic symptoms of abstinence syndrome (withdrawal symptoms) after naloxone administration.
D. Hyperventilation, depression, and constipation: These are not typical signs of abstinence syndrome.
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