A nurse is teaching a client about the adverse effects of nonsteroidal anti-inflammatory drugs (NSAIDs). Which of the following adverse effects should the nurse include in the teaching?

C) Correct. Sucralfate (Carafate) forms a protective barrier over the ulcer, allowing it to heal. However, it can interact with antacids, reducing its effectiveness. Therefore, the client should avoid taking antacids within 30 minutes before or after sucralfate administration.

A) Incorrect. Sucralfate should be taken on an empty stomach, but this does not necessarily mean it needs to be taken in the morning before breakfast.

B) Incorrect. Sucralfate should be swallowed whole without chewing. Chewing the medication is not necessary and may interfere with its effectiveness.

D) Incorrect. Sucralfate can be taken multiple times a day, depending on the healthcare provider's instructions. It does not necessarily need to be taken at bedtime.

C) Correct. Gastrointestinal bleeding is a potential adverse effect of NSAID use. NSAIDs can cause irritation and damage to the lining of the stomach and intestines, leading to bleeding and ulcers.

A) Incorrect. Constipation is not a common adverse effect of NSAIDs. Instead, NSAIDs can cause gastrointestinal disturbances such as diarrhea or abdominal pain.

B) Incorrect. Hypotension is not a typical adverse effect of NSAIDs. However, some individuals may experience fluid retention and edema, which can lead to elevated blood pressure.

D) Incorrect. Bronchospasm is not directly associated with NSAIDs. However, individuals with a history of aspirin sensitivity or asthma may experience bronchospasm as a hypersensitivity reaction to NSAIDs.