A nurse is teaching a client with a new prescription for metformin (Glucophage). Which of the following findings should the nurse instruct the client to report as an adverse effect of metformin? (Select All That Apply.)
Hypoglycemia
Somnolence
Fluid retention
Hyperglycemia
The Correct Answer is B
A. Metformin does not typically cause hypoglycemia because it works by decreasing hepatic glucose production and improving insulin sensitivity, not directly lowering blood sugar levels.
B. Somnolence could indicate lactic acidosis, a rare but serious adverse effect of metformin that warrants immediate medical attention.
C. Fluid retention is not a known adverse effect of metformin. Other medications, such as certain thiazolidinediones, are associated with this complication.
D. Hyperglycemia is not a typical adverse effect of metformin; instead, it helps manage blood glucose levels in clients with type 2 diabetes mellitus.
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Related Questions
Correct Answer is C
Explanation
A. Nausea is the symptom prochlorperazine is intended to treat, so its occurrence would suggest that the medication is not effective rather than being a complication.
B. Prolonged QT interval is not a typical complication of prochlorperazine; it is more commonly associated with medications like ondansetron.
C. Restlessness can indicate akathisia, a potential extrapyramidal side effect of prochlorperazine. This condition involves an intense feeling of restlessness and the need to move, commonly associated with dopamine antagonists.
D. Vomiting is a symptom treated by prochlorperazine and would likely occur due to inadequate control rather than being a complication of the drug itself.
Correct Answer is B
Explanation
A. Hyperglycemia: While metformin is used to manage blood glucose levels in clients with diabetes, its interaction with contrast dye does not directly lead to hyperglycemia. However, the risk for kidney injury, which can affect glucose regulation, is a concern.
B. Acute renal failure: This is correct. The combination of metformin and iodine-containing contrast dye increases the risk of acute renal failure, also known as contrast-induced nephropathy (CIN). This occurs because contrast agents can cause kidney damage, and metformin is excreted by the kidneys. If renal function is impaired, the buildup of metformin can lead to lactic acidosis.
C. Acute pancreatitis: While acute pancreatitis is a possible side effect of metformin in some individuals, the primary concern with iodine-containing contrast dye is renal failure, not pancreatitis.
D. Acute liver failure: Metformin is primarily metabolized by the kidneys, not the liver, and does not commonly cause liver failure. Renal failure is the more pressing concern with the use of contrast dye in clients taking metformin.
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