A patient has allergies and takes an antihistamine. The patient wants to know how the drug works. The nurse understands that antihistamines work because they are what?
Antidotes
Antagonists
Agonists
Activators
The Correct Answer is B
Choice A reason: Antidotes counteract specific toxins or drugs (e.g., naloxone for opioids). Antihistamines don’t neutralize allergens but block histamine receptors to reduce allergic symptoms like itching or sneezing. They target H1 or H2 receptors, not a toxin, making this choice incorrect for describing antihistamine mechanism of action.
Choice B reason: Antihistamines are antagonists, binding to histamine receptors (H1 or H2) without activating them, preventing histamine from triggering allergic responses like vasodilation or bronchoconstriction. This competitive inhibition reduces symptoms such as itching, sneezing, or gastric acid secretion, making this the correct choice for their pharmacological action.
Choice C reason: Agonists activate receptors to produce a response. Antihistamines block histamine receptors, not activate them, preventing allergic effects. Acting as agonists would mimic histamine, worsening symptoms like swelling or itching, which is opposite to their therapeutic role, making this choice incorrect.
Choice D reason: Activators is a vague term not used in pharmacology to describe drug action. Antihistamines specifically act as receptor antagonists, not general activators. They inhibit histamine effects without stimulating other pathways, making this choice inaccurate for explaining the mechanism of antihistamines in allergy management.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Furosemide, a loop diuretic, promotes potassium excretion, risking hypokalemia. The patient’s potassium level (3.1 mEq/L) is below normal (3.5-5.0 mEq/L), indicating hypokalemia, which can cause arrhythmias. Administering Lasix without addressing this could worsen the electrolyte imbalance, making this choice unsafe and incorrect.
Choice B reason: Oxygen administration addresses respiratory issues, not electrolyte imbalances like hypokalemia (3.1 mEq/L) caused by furosemide. There’s no indication of hypoxia in the lab results or scenario. This action doesn’t correct the potassium deficit or prevent further depletion, making it irrelevant and incorrect.
Choice C reason: Furosemide exacerbates hypokalemia (patient’s potassium: 3.1 mEq/L), risking cardiac arrhythmias or muscle weakness. Holding the dose prevents further potassium loss, and notifying the physician allows for correction (e.g., potassium supplements) and reassessment of therapy, making this the safest and most appropriate action.
Choice D reason: A 24-hour urine collection assesses renal function or output but doesn’t address the immediate concern of hypokalemia (3.1 mEq/L) caused by furosemide. This test is irrelevant to correcting the electrolyte imbalance or preventing further depletion, making it an inappropriate action in this scenario.
Correct Answer is D
Explanation
Choice A reason: Pseudoephedrine, a decongestant, relieves nasal congestion by vasoconstriction but doesn’t address inflammation or histamine-mediated symptoms like sneezing or itching in rhinitis. It’s less effective than intranasal corticosteroids, which target the underlying allergic response, making this choice less optimal for comprehensive rhinitis treatment.
Choice B reason: Intranasal cromolyn sodium stabilizes mast cells, reducing histamine release, but it’s less effective than corticosteroids for rhinitis. Atrovent (ipratropium) is incorrectly referenced here, as it treats rhinorrhea, not inflammation. Corticosteroids like fluticasone are preferred, making this choice incorrect for optimal treatment.
Choice C reason: Propranolol, a beta-blocker, treats hypertension and cardiac conditions, not rhinitis. It has no effect on allergic inflammation, histamine, or nasal congestion. Its use in rhinitis could worsen symptoms by causing bronchoconstriction in asthmatics, making this choice inappropriate and incorrect.
Choice D reason: Fluticasone propionate, an intranasal corticosteroid, reduces inflammation, edema, and histamine effects in seasonal and perennial rhinitis. It targets the allergic cascade, decreasing nasal congestion, sneezing, and itching, making it the most effective and guideline-recommended treatment, thus the correct choice for rhinitis management.
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