A patient who has been diagnosed with depression asks why the provider has not ordered a monoamine oxidase (MAO) inhibitor to treat the disorder. The nurse will explain to the patient that MAO inhibitors

are no longer approved for treating depression.

are more expensive than other antidepressants.

require strict dietary restrictions.

can cause profound hypotension.

Answer and Explanation

The Correct Answer is C

A) Are no longer approved for treating depression: MAO inhibitors (MAOIs) are still approved and used to treat depression, especially in cases where other medications have not been effective. They are not considered obsolete, though their use has become less common due to the availability of safer, more tolerable options. This is not the primary reason why MAOIs may not be prescribed.

B) Are more expensive than other antidepressants: While cost can be a factor in medication choice, it is not the primary reason why MAO inhibitors are less frequently prescribed for depression. There are other more significant concerns, such as side effects and dietary restrictions, that make other medications a preferred first-line choice.

C) Require strict dietary restrictions: This is the most accurate explanation. MAO inhibitors can cause dangerous interactions with certain foods that contain high levels of tyramine, such as aged cheeses, cured meats, and fermented products. Consuming these foods while on an MAOI can lead to a hypertensive crisis, which is a life-threatening condition. Because of these dietary restrictions, patients on MAOIs must adhere to a strict diet, which can be challenging to manage.

D) Can cause profound hypotension: While hypotension can occur as a side effect of MAOIs, it is not the most significant concern. The more serious risk with MAOIs is the potential for a hypertensive crisis due to dietary interactions with tyramine-containing foods, rather than hypotension. Therefore, the dietary restrictions are a more pressing issue than the risk of hypotension.

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Correct Answer is D

Explanation

A) “Alzheimer disease affects memory but not personality.”
While memory loss is one of the hallmark symptoms of Alzheimer’s disease, the condition also significantly impacts other cognitive functions, including personality and behavior. As the disease progresses, patients often experience changes in mood, behavior, and personality, such as increased irritability, depression, or aggression.

B) “With proper treatment, symptoms of this disease can be arrested.”
Currently, there is no cure for Alzheimer’s disease, and while some treatments (like cholinesterase inhibitors) can help manage symptoms temporarily or slow their progression, the disease itself is not arrestable. The goal of treatment is to manage symptoms and improve quality of life, but it cannot stop the disease from advancing.

C) “The onset of Alzheimer disease is usually between 65 and 75 years.”
While Alzheimer’s disease typically affects older adults, this statement is too narrow. Alzheimer’s disease can begin earlier, sometimes in individuals in their 50s or 60s, particularly in cases of early-onset Alzheimer’s. The average age of onset for most people is around 65, but there is variability.

D) “Alzheimer disease is a chronic, progressive condition.”
Alzheimer’s disease is indeed chronic (lasting for years) and progressive (it worsens over time). It gradually destroys brain cells, leading to a decline in cognitive function, including memory, thinking, and reasoning skills. This is the fundamental nature of the disease

A. Norepinephrine B. Decarboxylase C. Catecholamine D. Acetylcholinesterase

Correct Answer is D

Explanation

A) Norepinephrine: Norepinephrine is a neurotransmitter primarily involved in the sympathetic nervous system. It is not involved in terminating the stimulation caused by acetylcholine. Norepinephrine acts on adrenergic receptors, whereas acetylcholine primarily acts on cholinergic receptors.
B) Decarboxylase: Decarboxylase is an enzyme that plays a role in the synthesis of certain neurotransmitters, including dopamine, but it does not have a role in terminating the action of acetylcholine at the effector cell. It is unrelated to the termination of acetylcholine signaling.
C) Catecholamine: Catecholamines (such as dopamine, norepinephrine, and epinephrine) are a group of neurotransmitters involved in the sympathetic nervous system. While they play a role in synaptic transmission, they are not responsible for breaking down acetylcholine or terminating its effects. Their primary function is in adrenergic signaling.
D) Acetylcholinesterase: Acetylcholinesterase is the correct enzyme. It is responsible for breaking down acetylcholine (ACh) in the synaptic cleft after it has stimulated the effector cell. By hydrolyzing acetylcholine into acetate and choline, acetylcholinesterase effectively terminates the signal and allows the effector cell's membrane to repolarize. This action prevents continuous stimulation and ensures proper function of the cholinergic system.

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A patient who has been diagnosed with depression asks why the provider has not ordered a monoamine oxidase (MAO) inhibitor to treat the disorder. The nurse will explain to the patient that MAO inhibitors

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is providing teaching for the family of a patient who has been newly diagnosed with Alzheimer disease (AD). Which statement by the family member indicates understanding of the teaching?

Correct Answer is D

Explanation

After the effector cell has being stimulated by acetylcholine (ACh), what enzyme stop the stimulation and allows the effector membrane to repolarize?

Correct Answer is D

Explanation

When there is stimulation of the sympathetic nervous system (SNS), blood is diverted away from the gastrointestinal (GI) tract. What might the nurse assess that would indicate this diversion of blood flow to the GI tract?

In contrast to the sympathetic nervous system, the functions of the parasympathetic nervous system include:

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When hormones, formed within a cell, move across the cell membrane, the process is call what?

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Which of these is a neurotransmitter?

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