A patient with septic shock has a BP of 70/46 mm Hg. pulse of 136 beats/min, respirations of 32 breaths/min, temperature of 104" F, and blood glucose of 246 mg/dL. Which intervention ordered by the health care provider should the nurse implement first?

D Normal saline bolus administration is indicated for hypovolemia or inadequate intravascular volume, which can lead to decreased cardiac output and hypotension. In this scenario, the client has an amber urine output of 45ml in the last 3 hours, indicating decreased urine output and potential hypovolemia. The elevated blood pressure (170/67 mmHg) suggests possible volume overload or fluid retention, but the decreased urine output raises concerns for inadequate intravascular volume. Therefore, administering a normal saline bolus may be the first priority to optimize intravascular volume and improve cardiac output.

A Isosorbide mononitrate is a vasodilator commonly used in the treatment of heart failure and angina. It helps reduce preload and afterload, thereby decreasing the workload on the heart. However, in this scenario, the client's blood pressure is elevated (170/67 mmHg), and there is no indication of acute decompensation or pulmonary congestion. Therefore, isosorbide PO may not be the first priority medication at this time.

B Nitroglycerin is a potent vasodilator commonly used to manage acute heart failure exacerbations and acute coronary syndromes. It helps reduce preload and afterload, improving cardiac output and relieving symptoms of heart failure. In this scenario, the client's blood pressure is elevated, but the heart rate is normal, and there are no signs of acute decompensation. Therefore, initiating a nitroglycerin drip may not be the first priority unless the client develops symptoms of acute decompensation or pulmonary congestion.

C Dopamine is a vasopressor medication that can be used to increase blood pressure and cardiac output in patients with hypotension or shock. However, in this scenario, the client's blood pressure is elevated (170/67 mmHg), and there is no evidence of hypotension. Therefore, initiating a dopamine drip may not be appropriate at this time and could potentially exacerbate hypertension.

B. stroke volume is the amount of blood ejected from the left ventricle with each contraction (systole) of the heart. Changes in stroke volume directly affect cardiac output. An increase in stroke volume leads to an increase in cardiac output, while a decrease in stroke volume results in a decrease in cardiac output. Factors that can affect stroke volume include preload, afterload, and contractility of the heart.

C. Heart rate refers to the number of heartbeats per minute. Heart rate directly affects cardiac output by determining how frequently the heart contracts and pumps blood. An increase in heart rate (tachycardia) leads to an increase in cardiac output, while a decrease in heart rate (bradycardia) results in a decrease in cardiac output. Factors such as sympathetic and parasympathetic nervous system activity, hormones, and medications can influence heart rate.

A. Respiratory rate does not directly affect stroke volume or heart rate but changes in respiratory rate can indirectly impact cardiac output through their effects on venous return and preload.

D. Blood pressure represents the force exerted by the blood against the walls of the arteries. While blood pressure does not directly affect cardiac output, it is influenced by cardiac output and systemic vascular resistance (SVR).