After receiving Nembutal PO at bedtime, a client is wide awake all night instead of going to sleep. What kind of adverse reaction to a drug does this situation represent?
Toxic effect
Drug allergy
Idiosyncrasy
Drug tolerance
The Correct Answer is C
Choice A reason: Toxic effects involve overdose symptoms like coma; staying awake isn’t toxicity, as Nembutal’s sedative intent is reversed, not exaggerated, in this reaction.
Choice B reason: Drug allergy causes immune responses (e.g., rash); insomnia isn’t allergic, but a paradoxical effect, differing from hypersensitivity reactions entirely.
Choice C reason: Idiosyncrasy is an unexpected reaction; Nembutal, a barbiturate, should sedate, but wakefulness is an abnormal, individual response, fitting this category precisely.
Choice D reason: Tolerance reduces efficacy over time; this acute, opposite reaction to a sedative isn’t tolerance, but an immediate, unpredictable drug response.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Right patient ensures identity verification; errors here cause harm via misadministration, as drugs affect individuals differently based on physiology and condition.
Choice B reason: Right drug prevents wrong medication errors; each drug’s pharmacokinetics targets specific issues, and mistakes disrupt therapy or cause adverse reactions.
Choice C reason: Color isn’t a standard right; it’s not a reliable identifier, as formulations vary, and clinical safety relies on name, dose, and route, not appearance.
Choice D reason: Right route ensures correct delivery (e.g., IV vs. oral); wrong routes alter bioavailability and onset, risking toxicity or inefficacy per drug design.
Choice E reason: Right time optimizes efficacy; timing aligns with drug half-life and patient needs, preventing under- or overdosing from improper administration schedules.
Correct Answer is A
Explanation
Choice A reason: Alcohol and hepatitis C impair liver function; acetaminophen’s metabolite NAPQI accumulates, causing hepatotoxicity in an already compromised organ.
Choice B reason: COPD and smoking affect lungs, not liver; acetaminophen metabolism is minimally impacted, posing lower hepatic risk compared to liver disease states.
Choice C reason: Renal disease affects drug excretion, not liver metabolism; acetaminophen’s hepatic load is unchanged, making liver damage less likely here.
Choice D reason: Prostate issues involve urinary tract; liver metabolism of acetaminophen remains intact, with no heightened risk of hepatotoxicity from this condition.
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