An older client may be at higher risk for medication toxicity due to which of the following physiological changes associated with aging?
Reduced hepatic blood flow
Reduced body fat
Increased glomerular filtration rate
Increased gastric motility
The Correct Answer is A
Reduced hepatic blood flow can decrease the metabolism and excretion of many drugs, requiring that doses of some drugs be decreased ². This can increase the risk of medication toxicity in older adults.
Option B is not correct because reduced body fat is not a physiological change associated with aging.
Option C is not correct because the glomerular filtration rate decreases with age ².
Option D is not correct because gastric motility decreases with age ².

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
In pharmacodynamics, receptors play a crucial role in mediating the effects of medications ¹. Medications must bind with receptors to mimic or block the actions of the body's own regulatory molecules ¹. This binding can activate or inhibit the receptor, leading to a biological response ¹.
Option B is incorrect because activation of the receptor by the medication does not necessarily cause the cell to develop a new function.
Option C is incorrect because receptors do not start the process of metabolism of the medication by the liver.
Option D is incorrect because binding a medication to a receptor does not necessarily make the medication more selective to that type of receptor.

Correct Answer is B
Explanation
It is important for the nurse to understand why the client is refusing to take the medication. There may be underlying reasons such as side effects, fear, or misunderstanding about the medication. By investigating and addressing these concerns, the nurse can help the client make an informed decision about their treatment.
Option A may not address the underlying reasons for noncompliance and could be perceived as confrontational.
Option C may be appropriate after understanding the reasons for noncompliance and discussing them with the provider.
Option D may also be appropriate in some cases, but it is important to first understand the reasons for noncompliance before involving a social worker.
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