An older client may be at higher risk for medication toxicity due to which of the following physiological changes associated with aging?
Reduced hepatic blood flow
Reduced body fat
Increased glomerular filtration rate
Increased gastric motility
The Correct Answer is A
Reduced hepatic blood flow can decrease the metabolism and excretion of many drugs, requiring that doses of some drugs be decreased ². This can increase the risk of medication toxicity in older adults.
Option B is not correct because reduced body fat is not a physiological change associated with aging.
Option C is not correct because the glomerular filtration rate decreases with age ².
Option D is not correct because gastric motility decreases with age ².
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Anticholinergic medications can be used to treat extrapyramidal symptoms (EPS) such as tremors and shuffling gait that can occur as side effects of first-generation antipsychotics ¹².
Option A is not correct because a direct dopamine antagonist would not be used to treat EPS.
Option B is not correct because increasing the dose of the antipsychotic medication could worsen EPS.
Option C is not correct because withholding the medication for two days could lead to a relapse of the underlying condition being treated by the antipsychotic.
Correct Answer is C
Explanation
A half-life is the time it takes for the concentration of a drug in the body to decrease by half. In this case, the medication has an 8-hour half-life, so after 8 hours, the concentration of the medication in the client's body would be reduced to 400mg (half of the initial dose of 800mg). After another 8 hours (16 hours total), the concentration would be reduced to 200mg. After another 8 hours (24 hours total), the concentration would be reduced to 100mg.
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