An older client may be at higher risk for medication toxicity due to which of the following physiological changes associated with aging?

Reduced hepatic blood ﬂow

Reduced body fat

Increased glomerular filtration rate

Increased gastric motility

Answer and Explanation

The Correct Answer is A

Reduced hepatic blood flow can decrease the metabolism and excretion of many drugs, requiring that doses of some drugs be decreased ². This can increase the risk of medication toxicity in older adults.
Option B is not correct because reduced body fat is not a physiological change associated with aging.
Option C is not correct because the glomerular filtration rate decreases with age ².
Option D is not correct because gastric motility decreases with age ².

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Correct Answer is A

Explanation

Teratogenic refers to an agent or factor that causes malformation of an embryo ¹. It is something that can interfere with normal fetal development and cause congenital disabilities ³. Drugs, alcohol, chemicals, and toxic substances are examples of teratogens ³.
Option B is not correct because teratogenic specifically refers to harm caused to a fetus, not kidney damage.
Option C is not correct because teratogenic does not refer to a medication acting in the opposite manner than expected.
Option D is not correct because teratogenic does not refer to a medication causing an additive eﬀect.

A. To help prevent sexual dysfunction B. To avoid weight gain and other gastrointestinal (GI) eﬀects C. To prevent the risk of serotonin syndrome D. To reduce the risk of suicide with overdose

Correct Answer is D

Explanation

A selective serotonin reuptake inhibitor (SSRI) would be chosen as a first-line treatment option over a tricyclic antidepressant (TCA) for several reasons, including reducing the risk of suicide with overdose ³. TCAs have a higher potential for serious or fatal toxicity when taken in large amounts compared to SSRIs ³.
Option A is incorrect because SSRIs can cause sexual dysfunction as a side effect.
Option B is incorrect because both SSRIs and TCAs can cause weight gain and gastrointestinal (GI) eﬀects.
Option C is incorrect because SSRIs can increase the risk of serotonin syndrome when taken with other medications that affect serotonin levels.

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An older client may be at higher risk for medication toxicity due to which of the following physiological changes associated with aging?

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Naxlex Comprehensive Predictor Exams

A medication is described as having teratogenic side effects. The nurse understands that teratogenic is defined as which of the following?

Correct Answer is A

Explanation

The nurse is caring for a client being treated for depression. The nurse understands that a selective serotonin reuptake inhibitor (SSRI) would be chosen as a first-line treatment option over a tricyclic antidepressant (TCA) for which of the following reasons?

Correct Answer is D

Explanation

A client asks what is meant by the statement "tolerance can occur when taking anxiolytics." The nurse understands that tolerance means which of the following?

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