Elevated anti-diuretic (ADH) levels and hyponatremia is seen with which of the following disorders?
Diabetes Insipidus
Acromegaly
Addisons disease
Syndrome of inappropriate Antiduretic Hormone
The Correct Answer is D
A. Diabetes Insipidus is associated with reduced ADH levels, leading to excessive urination and dehydration, not hyponatremia.
B. Acromegaly results from excessive growth hormone (not ADH) secretion, causing abnormal growth of tissues and bones.
C. Addison's disease involves the adrenal glands and the insufficient production of cortisol and aldosterone, not ADH-related hyponatremia.
D. Syndrome of Inappropriate Antidiuretic Hormone (SIADH).
SIADH is a disorder characterized by the excessive release of antidiuretic hormone (ADH) from the posterior pituitary gland, leading to increased water reabsorption by the kidneys. This results in diluted blood and hyponatremia (low sodium levels) due to the retention of water. Patients with SIADH often experience fluid overload and related symptoms.
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Related Questions
Correct Answer is ["B","C","D"]
Explanation
A. Metabolic alkalosis is not a common acid-base imbalance associated with ARF. Instead, metabolic acidosis is more commonly observed due to the retention of metabolic waste products.
B. Water and sodium (Na) retention: In ARF, the kidneys are unable to effectively filter and excrete waste products and excess fluids. This leads to the retention of water and sodium, contributing to fluid overload.
C. Anemia: ARF can lead to decreased erythropoietin production by the kidneys, which can result in anemia due to reduced red blood cell production.
D. Hyperkalemia: The impaired kidney function in ARF may result in the inability to regulate potassium levels. Elevated levels of potassium (hyperkalemia) can be a dangerous complication.
E. Increased urinary output is not a typical finding in ARF. Instead, the hallmark of ARF is a reduction in urine output or oliguria.
Correct Answer is A
Explanation
A. Bone marrow transplantation.
Severe aplastic anemia is a condition characterized by a significant reduction in the number of blood cells produced by the bone marrow. The primary treatment for severe aplastic anemia is a bone marrow transplantation, also known as a stem cell transplant. This procedure involves replacing the patient's dysfunctional bone marrow with healthy bone marrow or stem cells from a suitable donor. This is done to restore normal blood cell production.
Option B (Exchange transfusion) is not the primary treatment for severe aplastic anemia but may be used in certain cases to manage complications or specific symptoms.
Option C (Liver transplantation) is not a treatment for severe aplastic anemia, as this condition primarily affects the bone marrow and blood cell production.
Option D (Administration of intravenous immunoglobulin) is not the primary treatment for severe aplastic anemia but may be used in some cases to manage complications, such as infections. However, it does not address the underlying cause of the disease, which is the failure of the bone marrow to produce enough blood cells.
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