For each of the following potential antihypertensive medications, indicate whether it is recommended or not recommended for use in a pregnant client.
Methyldopa.
Lisinopril.
Labetalol.
Losartan.
Hydralazine.
The Correct Answer is {"A":{"answers":"A"},"B":{"answers":"B"},"C":{"answers":"A"},"D":{"answers":"B"},"E":{"answers":"A"}}
Choice A rationale
Methyldopa is a first-line antihypertensive for pregnancy-induced hypertension. It is safe, effective, and preferred due to its minimal placental transfer and limited fetal impact.
Choice B rationale
Lisinopril, an ACE inhibitor, is contraindicated in pregnancy due to teratogenic risks, including fetal renal malformations and oligohydramnios. It poses significant dangers to fetal health.
Choice C rationale
Labetalol, a combined alpha and beta-blocker, is recommended for managing hypertensive crises in pregnancy. It offers effective blood pressure control with a favorable safety profile.
Choice D rationale
Losartan, an angiotensin II receptor blocker, is not recommended in pregnancy. It risks fetal toxicity, including kidney dysfunction and growth restriction, similar to ACE inhibitors.
Choice E rationale
Hydralazine is a vasodilator safe for pregnancy. It is recommended for treating severe hypertensive emergencies, particularly in preeclampsia, due to its efficacy in reducing vascular resistance.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Amnioinfusion addresses variable decelerations by relieving cord compression; however, discontinuing oxytocin to prevent further decelerations precedes procedural interventions for labor augmentation.
Choice B rationale
Vaginal/speculum exams are not the priority during recurrent variable decelerations as they delay immediate measures addressing cord compression and fetal oxygenation concerns.
Choice C rationale
Discontinuing oxytocin reduces uterine contractions, alleviating cord compression and improving fetal oxygenation, which is the first step in managing recurrent variable decelerations of fetal heart rate.
Choice D rationale
Instructions about potential birth preparation are important but not immediate for addressing variable decelerations, as they do not directly resolve underlying cord compression concerns. .
Correct Answer is A
Explanation
Choice A rationale
Ibuprofen can interact with various over-the-counter medications, including anticoagulants and corticosteroids, which may increase risks of side effects like gastrointestinal bleeding or reduced efficacy, necessitating careful assessment of concurrent drug use.
Choice B rationale
Ibuprofen use is contraindicated in individuals with gastric issues, such as peptic ulcers, as it inhibits prostaglandins, reducing mucosal protection and increasing risks of gastrointestinal perforation and bleeding.
Choice C rationale
Assessing contraception use is irrelevant to ibuprofen administration because ibuprofen lacks teratogenic effects or interference with hormonal contraception and poses no pregnancy-related risks at therapeutic doses.
Choice D rationale
While ibuprofen can elevate blood pressure via prostaglandin inhibition, this is secondary and less clinically significant compared to immediate concerns like drug interactions or gastric side effects.
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