Gestational diabetes is: (Select All that Apply.)

Choice A reason: The neck is the most common site where individuals with Hodgkin Lymphoma (HL) present with nontender enlarged lymph nodes. These lymph nodes are typically firm and rubbery in texture. The cervical lymph nodes are often affected first in HL, making the neck a primary area of concern for this type of lymphoma. Early detection and biopsy of these lymph nodes can help in diagnosing HL.

Choice B reason: While the abdomen can be involved in Hodgkin Lymphoma, it is not the most common initial presentation site. Involvement of the abdominal lymph nodes typically occurs at later stages of the disease. Enlarged lymph nodes in the abdomen can be detected through imaging studies but are less accessible for physical examination compared to those in the neck.

Choice C reason: The kidney is not a typical site for lymph node involvement in Hodgkin Lymphoma. HL primarily affects the lymphatic system, including lymph nodes, spleen, and other lymphoid tissues. Direct involvement of the kidney is rare and usually occurs in advanced stages of the disease.

Choice D reason: The spleen is a lymphoid organ that can be involved in Hodgkin Lymphoma, especially in more advanced stages. However, it is not the primary site where nontender enlarged lymph nodes are first detected. Enlargement of the spleen (splenomegaly) can occur due to the spread of HL, but the initial presentation is usually in the lymph nodes of the neck.

Choice A reason: Most patients with CNS tumors do not develop metastatic disease. Central nervous system (CNS) tumors, including brain tumors, typically do not metastasize outside the CNS. Instead, they grow and exert pressure on adjacent brain structures, leading to neurological symptoms.

Choice B reason: While brain tumors can be very deadly, the TNM classification system is not avoided due to the lethality of the tumors. The main reason for not using the TNM system is because the classification criteria do not align well with the unique aspects of brain tumors.

Choice C reason: Tumor size is less relevant than the location and histology for brain tumors. The location of the tumor within the brain and its histological characteristics (e.g., type, grade, and molecular features) are more critical for prognosis and treatment planning. Brain tumors can cause significant clinical issues even when small, depending on their location.

Choice D reason: Brain tumors can have a poor prognosis, but this is not the reason the TNM classification is not used. The classification system's limitation is primarily due to the fact that brain tumors' behavior and treatment considerations depend more on their location and histological features than on tumor size, nodal involvement, and metastasis, which are the focus of the TNM system.