How does Paget's disease differ from osteoporosis?
Paget's disease is characterized by decreased bone density, while osteoporosis is associated with increased bone density.
Paget's disease primarily affects trabecular bone, while osteoporosis affects cortical bone.
Paget's disease involves abnormal bone remodeling and increased bone turnover, while osteoporosis involves decreased bone formation and increased bone resorption.
Paget's disease is an autoimmune disorder, while osteoporosis is caused by hormonal imbalances.
The Correct Answer is C
The main difference between Paget's disease and osteoporosis is in the underlying bone remodeling. Paget's disease is characterized by increased bone turnover and disordered bone formation, while osteoporosis involves decreased bone formation and increased bone resorption.
a. Paget's disease is characterized by decreased bone density, while osteoporosis is associated with increased bone density: This statement is incorrect. In Paget's disease, bone density can be normal or increased due to the disordered bone remodeling.
b. Paget's disease primarily affects trabecular bone, while osteoporosis affects cortical bone: This statement is incorrect. Both Paget's disease and osteoporosis can affect both trabecular and cortical bone.
d. Paget's disease is an autoimmune disorder, while osteoporosis is caused by hormonal imbalances: This statement is incorrect. Paget's disease is not an autoimmune disorder, and osteoporosis is not solely caused by hormonal imbalances. Both conditions have complex multifactorial etiologies.
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Related Questions
Correct Answer is C
Explanation
The femur, which is the thigh bone, is often affected in Paget's disease. The condition commonly involves the axial skeleton, such as the skull, spine, and pelvis, as well as the long bones like the femur.
a. Humerus (arm bone): The humerus can be affected in Paget's disease, but it is not as commonly involved as the femur.
b. Radius (forearm bone): The radius can be affected in Paget's disease, but it is not as commonly involved as the femur.
d. Fibula (lower leg bone): The fibula can be affected in Paget's disease, but it is not as commonly involved as the femur.
Correct Answer is C
Explanation
Individuals with Paget's disease should be encouraged to engage in walking and low-impact exercises to promote bone health. These activities are less likely to cause fractures or stress on the bones while still supporting bone strength and density.
a. Participating in high-impact sports: High-impact sports can put excessive stress on the bones and increase the risk of fractures in individuals with Paget's disease. It is not recommended.
b. Limiting physical activity to avoid fractures: While excessive physical activity may need to be moderated to prevent fractures, limiting all physical activity is not advisable. Moderate exercise is essential for overall health and bone strength.
d. Heavy weightlifting: Heavy weightlifting can increase the risk of fractures in individuals with Paget's disease. It is not recommended, as it can put excessive stress on the bones.
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