How does Paget's disease differ from osteoporosis?
Paget's disease is characterized by decreased bone density, while osteoporosis is associated with increased bone density.
Paget's disease primarily affects trabecular bone, while osteoporosis affects cortical bone.
Paget's disease involves abnormal bone remodeling and increased bone turnover, while osteoporosis involves decreased bone formation and increased bone resorption.
Paget's disease is an autoimmune disorder, while osteoporosis is caused by hormonal imbalances.
The Correct Answer is C
The main difference between Paget's disease and osteoporosis is in the underlying bone remodeling. Paget's disease is characterized by increased bone turnover and disordered bone formation, while osteoporosis involves decreased bone formation and increased bone resorption.
a. Paget's disease is characterized by decreased bone density, while osteoporosis is associated with increased bone density: This statement is incorrect. In Paget's disease, bone density can be normal or increased due to the disordered bone remodeling.
b. Paget's disease primarily affects trabecular bone, while osteoporosis affects cortical bone: This statement is incorrect. Both Paget's disease and osteoporosis can affect both trabecular and cortical bone.
d. Paget's disease is an autoimmune disorder, while osteoporosis is caused by hormonal imbalances: This statement is incorrect. Paget's disease is not an autoimmune disorder, and osteoporosis is not solely caused by hormonal imbalances. Both conditions have complex multifactorial etiologies.
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Related Questions
Correct Answer is D
Explanation
Bowing of long bones is a characteristic skeletal finding in Paget's disease. The abnormal bone remodeling can lead to bone bowing and misalignment, particularly in the long bones of the arms and legs.
a. Scoliosis: Scoliosis is a lateral curvature of the spine and is not directly associated with Paget's disease. It may be related to other musculoskeletal conditions.
b. Kyphosis: Kyphosis is an excessive forward curvature of the spine, often seen in conditions like osteoporosis, but it is not a primary finding in Paget's disease.
c. Bone tenderness: Bone tenderness may be present due to the bone inflammation and pain associated with Paget's disease, but it is not a specific skeletal finding.
Correct Answer is D
Explanation
Paget's disease most commonly affects older adults, typically those over the age of 60. While it can occur at any age, the prevalence increases with age.
a. Children and adolescents: Paget's disease is rare in children and adolescents. It is more commonly seen in older individuals.
b. Young adults (ages 20-40): While Paget's disease can occur in young adults, it is less common in this age group compared to older adults.
c. Middle-aged adults (ages 40-60): While Paget's disease can occur in middle-aged adults, it is more commonly seen in older individuals.
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