Which cell type is primarily responsible for the increased bone resorption seen in Paget's disease?
Osteocytes
Osteoblasts
Osteoclasts
Osteoprogenitor cells
The Correct Answer is C
Osteoclasts are the primary cell type responsible for bone resorption in Paget's disease. These cells become overactive, leading to excessive bone breakdown, which is a hallmark of the condition.
a. Osteocytes: Osteocytes are mature bone cells embedded in the bone matrix. While they play a role in maintaining bone health, they are not directly responsible for bone resorption.
b. Osteoblasts: Osteoblasts are bone-forming cells. In Paget's disease, they attempt to repair the resorbed bone but their activity is disordered, leading to structurally abnormal bone formation.
d. Osteoprogenitor cells: Osteoprogenitor cells are undifferentiated cells that can differentiate into osteoblasts. They are not directly involved in the increased bone resorption seen in Paget's disease.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Joint stiffness is a common symptom in patients with Paget's disease, especially when bone deformities are present. The nurse should closely monitor for any changes in joint mobility and range of motion, as joint stiffness can impact the patient's ability to perform daily activities.
a. Weight gain: Weight gain is not a specific symptom of Paget's disease. It is not directly related to the condition.
c. Hyperactivity: Hyperactivity is not a characteristic symptom of Paget's disease. The condition primarily affects bone structures.
d. Blurred vision: Blurred vision is not associated with Paget's disease. It is not a symptom commonly observed in individuals with the condition.
Correct Answer is C
Explanation
Individuals with Paget's disease should be encouraged to engage in walking and low-impact exercises to promote bone health. These activities are less likely to cause fractures or stress on the bones while still supporting bone strength and density.
a. Participating in high-impact sports: High-impact sports can put excessive stress on the bones and increase the risk of fractures in individuals with Paget's disease. It is not recommended.
b. Limiting physical activity to avoid fractures: While excessive physical activity may need to be moderated to prevent fractures, limiting all physical activity is not advisable. Moderate exercise is essential for overall health and bone strength.
d. Heavy weightlifting: Heavy weightlifting can increase the risk of fractures in individuals with Paget's disease. It is not recommended, as it can put excessive stress on the bones.
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