How does the emergency department nurse caring for a critically ill with septic shock recognize that severe tissue hypoxia is present?

Partial thromboplastin time 64 seconds

Lactate 9.0 mmol/L

Potassium 2.8 mEq/L (2.8 mmol/L)

PaCO2 58 mm Hg

Answer and Explanation

The Correct Answer is B

Lactate is a by-product of anaerobic metabolism that accumulates when there is insufficient oxygen supply to meet cellular metabolic demands. In the context of severe tissue hypoxia, such as in septic shock, the body may resort to anaerobic metabolism, leading to increased lactate production and elevated lactate levels in the blood.
Elevated lactate levels, typically above 4.0 mmol/L, are indicative of tissue hypoxia and inadequate oxygenation at the cellular level. Higher lactate levels, such as 9.0 mmol/L, suggest more severe tissue hypoxia and increased anaerobic metabolism.
A. Partial thromboplastin time (PTT) 64 seconds in (option A) is incorrect because: PTT is a laboratory test that evaluates the intrinsic pathway of the coagulation cascade. While coagulation abnormalities may occur in septic shock, PTT alone does not specifically indicate severe tissue hypoxia.
C. Potassium 2.8 mEq/L (2.8 mmol/L) (option C) is incorrect because Low potassium levels (hypokalemia) can be a concern in septic shock, but it does not directly indicate severe tissue hypoxia.
D. PaCO2 58 mm Hg in (option D) is incorrect because: PaCO2 refers to the partial pressure of carbon dioxide in arterial blood and is a measure of the respiratory status. While an elevated PaCO2 can be a sign of respiratory acidosis, it is not specific to severe tissue hypoxia.
Therefore, in a critically ill patient with septic shock, an elevated lactate level, such as 9.0 mmol/L, indicates severe tissue hypoxia and inadequate oxygenation at the cellular level

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Correct Answer is A

Explanation

Disseminated intravascular coagulation (DIC) is a condition characterized by both widespread activation of the coagulation system and excessive clotting, leading to the consumption of clotting factors and platelets. This results in a prothrombotic state, which can lead to organ dysfunction and bleeding manifestations.
Elevated D-dimer levels are a characteristic finding in DIC. D-dimer is a fibrin degradation product that is elevated when there is excessive fibrin formation and breakdown. Elevated D-dimer indicates ongoing fibrinolysis and activation of the clotting system.
B. Decreased prothrombin time in (option B) is incorrect because: DIC is characterized by consumption of clotting factors, which can result in prolongation of the prothrombin time (PT) as well as other coagulation tests.
C. Decreased partial thromboplastin time in (option C) is incorrect because Similar to the prothrombin time, the partial thromboplastin time (PTT) can also be prolonged in DIC due to the consumption of clotting factors.
D. Elevated fibrinogen level in (option D) is incorrect because, In DIC, there is consumption of fibrinogen along with other clotting factors. Therefore, elevated fibrinogen levels are not consistent with the pathophysiology of DIC.

A. SA node - AV node - bundle of his - bundle branches - Purkinje fibers. B. SA node - bundle of his -AV node - bundle branches - Purkinje fibers. C. SA node - AV node - bundle branches - Ventricles - Purkinje fibers. D. AV node-SA node - a bundle of his - bundle branches - Purkinje fibers.

Correct Answer is A

Explanation

This pathway represents the normal sequence of electrical impulses that coordinate the contraction and relaxation of the heart chambers.
The electrical signal originates from the sinoatrial (SA) node, which is often referred to as the natural pacemaker of the heart. It is located in the right atrium and generates the electrical impulses that initiate each heartbeat. From the SA node, the electrical signal travels to the atrioventricular (AV) node, which is located at the junction between the atria and ventricles.
After passing through the AV node, the electrical impulse travels through the bundle of His (also known as the atrioventricular bundle) and divides into the right and left bundle branches. These branches continue the conduction pathway and deliver the electrical signal to the Purkinje fibers.
The Purkinje fibers spread the electrical impulse rapidly throughout the ventricles, stimulating the contraction of the ventricular muscle and allowing for efficient pumping of blood out of the heart.
Therefore, the correct sequence of the normal conduction pathway in the heart is:
A. SA node - AV node - bundle of His - bundle branches - Purkinje fibers.

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How does the emergency department nurse caring for a critically ill with septic shock recognize that severe tissue hypoxia is present?

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