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Marie Garcia, age 67, reports that her chronic angina has been recurring even though she has been taking nitroglycerin sublingual tablets as prescribed. She tells the nurse that she used to store the tablets on a table by the window, and when she started to use a new batch of tablets, the problem subsided. What I would explain the ineffectiveness of the tablets?

Ms. Garcia developed unstable angina

Exposure to the elements (natural light) caused the drugs to lose their effectiveness

Ms. Garcia developed tolerance to the sublingual form of administration

Ms. Garcia did not follow the correct interval or duration of administration

Answer and Explanation

The Correct Answer is B

Explanation:

A. There is no evidence in the scenario to suggest that Ms. Garcia developed unstable angina.

B. Exposure to light, particularly sunlight, can degrade nitroglycerin, reducing its effectiveness over time.

C. There is no indication that Ms. Garcia developed tolerance to sublingual nitroglycerin in this scenario.

D. Ms. Garcia's storage method for the nitroglycerin tablets, not the interval or duration of administration, likely affected their effectiveness.

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Correct Answer is B

Explanation

A. Bile acid agents primarily work by binding to bile acids in the intestines, leading to increased excretion of bile acids and cholesterol, but they are not specifically indicated for reducing triglyceride levels.

B. Fibric acid agents, such as gemfibrozil and fenofibrate, are considered the drug of choice for decreasing triglyceride levels, primarily by increasing the breakdown of triglyceride-rich particles and reducing hepatic triglyceride production.

C. HMG-CoA reductase inhibitors (statins) primarily lower LDL cholesterol levels but may also have modest effects on triglyceride levels.

D. Statins primarily target LDL cholesterol levels and are not considered the first-line therapy specifically for reducing triglyceride levels.

A. Fever B. Tinnitus C. Bruising D. Rash.

Correct Answer is A

Explanation

A. Fever is one of the hallmark symptoms of serotonin syndrome, along with other signs such as agitation, confusion, rapid heart rate, dilated pupils, and sweating.

B. Tinnitus is not a typical symptom of serotonin syndrome but may indicate other issues or side effects.

C. Bruising is not a typical symptom of serotonin syndrome but may indicate other issues or side effects.

D. Rash is not a typical symptom of serotonin syndrome but may indicate other issues or side effects.

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What drug classification is considered the drug of choice to decrease triglyceride levels?

Correct Answer is B

Explanation

A nurse is collecting data from a client who has been taking sertraline (Zoloft) for the past 2 weeks. Which of the following data collection findings should alert the nurse to the possibility that the client is developing serotonin syndrome?

Correct Answer is A

Explanation

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