In the treatment of angina, the mechanism of action of an organic nitrate is:
Increased contractility and heart rate.
Slowed heart rate and decreased contractility of the heart.
Relaxation of arterial and venous smooth muscle.
Increased peripheral resistance.
The Correct Answer is C
A. Organic nitrates do not increase contractility and heart rate; they typically decrease myocardial oxygen demand.
B. Organic nitrates do not slow heart rate or decrease contractility of the heart.
C. The mechanism of action of organic nitrates in the treatment of angina is the relaxation of arterial and venous smooth muscle, leading to vasodilation and decreased myocardial oxygen demand.
D. Organic nitrates do not increase peripheral resistance; they typically cause vasodilation.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. ACE inhibitors primarily affect blood pressure and heart remodeling but do not directly decrease heart rate or contractility.
B. Vasodilators mainly lower blood pressure by expanding blood vessels and do not primarily affect heart rate or contractility.
C. Beta blockers decrease heart rate, contractility, and blood pressure, and are specifically used to improve survival after a heart attack by reducing the heart's workload and oxygen demand.
D. Diuretics primarily reduce blood pressure by decreasing blood volume but do not directly decrease heart rate or contractility.
Correct Answer is A
Explanation
A. High cholesterol can lead to the buildup of plaque in the arteries, which can narrow the blood vessels and decrease blood flow to the heart, increasing the risk of heart disease.
B. High cholesterol does not directly damage the heart muscle but can contribute to conditions like atherosclerosis, which can affect heart function.
C. High cholesterol does not directly thicken the blood but can contribute to the formation of blood clots when combined with other factors.
D. High cholesterol does not typically interfere with the conduction system of the heart but can contribute to conditions like coronary artery disease.
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