A client taking atorvastatin develops an increased serum creatine phosphokinase (CK) level. The nurse should assess the client for the onset of which problem?

Muscle tenderness.

Nausea and vomiting.

Excessive bruising.

Peripheral edema.

Answer and Explanation

The Correct Answer is A

Choice A reason: Muscle tenderness is a sign of myopathy, a rare but serious adverse effect of atorvastatin and other statins. Myopathy is characterized by muscle weakness, pain, and elevated CK levels. CK is an enzyme that is released when muscle tissue is damaged. The nurse should monitor the client for muscle tenderness and report any changes to the prescriber.

Choice B reason: Nausea and vomiting are common side effects of atorvastatin, but they are not related to CK levels. The nurse should advise the client to take the medication with food and fluids to minimize gastrointestinal discomfort.

Choice C reason: Excessive bruising is not a typical side effect of atorvastatin, nor is it associated with CK levels. The nurse should assess the client for other possible causes of bleeding, such as coagulation disorders, trauma, or drug interactions.

Choice D reason: Peripheral edema is not a common side effect of atorvastatin, and it is not related to CK levels. The nurse should assess the client for other signs of fluid retention, such as weight gain, shortness of breath, or jugular venous distension. The nurse should also check the client's blood pressure and heart rate, as peripheral edema may indicate heart failure or hypertension.

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Correct Answer is B

Explanation

The correct answer is b. Liver function laboratory results.

Choice A reason:

Weight change in the last month can be an important factor to consider for a patient's overall health and may be relevant in the context of depression, as significant weight changes can be a symptom of this condition. However, it is not the most critical piece of information before prescribing duloxetine. Duloxetine is not primarily metabolized by the kidneys, and while weight can affect dosing and efficacy, it is not the most crucial factor to consider before starting treatment.

Choice B reason:

Liver function laboratory results are crucial to obtain before prescribing duloxetine because duloxetine is extensively metabolized by the liver. The prescribing information for duloxetine warns of the potential for hepatotoxicity, and hepatic failure has been reported in some cases. Therefore, it is essential to ensure that the patient's liver function is normal before initiating therapy with duloxetine, as impaired liver function could lead to increased levels of the medication in the body and a higher risk of side effects.

Choice C reason:

Recent use of other antidepressants is important to consider avoiding drug interactions, particularly with monoamine oxidase inhibitors (MAOIs), which can lead to serious, life-threatening side effects if taken together with duloxetine. While this information is important, it is not as critical as liver function, because the primary concern with other antidepressants is the timing of medication changes rather than an absolute contraindication.

Choice D reason:

A family history of mental illness can provide valuable information for understanding a patient's background and potential genetic predispositions to certain conditions. However, this information does not directly impact the safety and initial prescribing of duloxetine. It may be more relevant for long-term treatment considerations and prognosis rather than immediate prescription safety.

A. Administer both prescribed medications as scheduled. B. Hold the calcium carbonate, but administer the calcitriol as scheduled. C. Hold both medications until contacting the healthcare provider. D. Hold the calcitriol, but administer the calcium carbonate as scheduled.

Correct Answer is C

Explanation

Choice A reason: Administering both prescribed medications as scheduled is not the appropriate action in this situation. The client's total calcium level is above the normal range of 9 to 10.5 mg/dL (2.25 to 2.62 mmol/L), indicating hypercalcemia. Hypercalcemia is a serious condition that can cause nausea, vomiting, constipation, confusion, kidney stones, and cardiac arrhythmias. Giving more calcitriol and calcium carbonate would worsen the client's condition and increase the risk of complications.

Choice B reason: Holding the calcium carbonate, but administering the calcitriol as scheduled is not the appropriate action in this situation. Calcium carbonate is a supplement that provides extra calcium to the body. Calcitriol is a synthetic form of vitamin D that helps the body absorb calcium from the intestines and kidneys. Both medications can increase the blood calcium level and cause hypercalcemia. The nurse should not give either medication without consulting the healthcare provider.

Choice C reason: Holding both medications until contacting the healthcare provider is the best action in this situation. The nurse should recognize that the client's total calcium level is dangerously high and report it to the healthcare provider as soon as possible. The healthcare provider may order to stop or adjust the doses of calcitriol and calcium carbonate, and prescribe other treatments to lower the blood calcium level, such as intravenous fluids, diuretics, or bisphosphonates.

Choice D reason: Holding the calcitriol, but administering the calcium carbonate as scheduled is not the appropriate action in this situation. Calcium carbonate is a supplement that provides extra calcium to the body. Giving more calcium carbonate to a client with hypercalcemia would increase the blood calcium level even more and cause more harm. The nurse should not give any medication that can raise the blood calcium level without consulting the healthcare provider.

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A client taking atorvastatin develops an increased serum creatine phosphokinase (CK) level. The nurse should assess the client for the onset of which problem?

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Naxlex Comprehensive Predictor Exams

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Explanation

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Explanation

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