Patient Data
The nurse is discussing the client's pain management with a student nurse. Choose the most likely options for the information missing from the statement(s) by selecting from the lists of options provided.
Morphine is a(n)
and it activates receptors and is used to relieve .The Correct Answer is {"dropdown-group-1":"C","dropdown-group-2":"A","dropdown-group-3":"C"}
The correct answer is:
Morphine is a(n) **pure opioid antagonist** and it activates **mu** receptors and is used to relieve **severe pain**.
Choice area A
Choice A reason:
A pure opioid antagonist is a drug that blocks the effects of opioids by binding to their receptors without activating them. Morphine is not a pure opioid antagonist, but a pure opioid agonist, which means it binds to and activates opioid receptors, producing analgesia and other effects. Therefore, choice A is incorrect.
Choice B reason:
An endogenous opioid is a naturally occurring substance in the body that binds to and activates opioid receptors, such as endorphins and enkephalins. Morphine is not an endogenous opioid, but an exogenous opioid, which means it is derived from an external source, such as the opium poppy. Therefore, choice B is incorrect.
Choice C reason:
A pure opioid antagonist is the correct term for morphine, as explained above. Therefore, choice C is correct.
Choice D reason:
A local anesthetic is a drug that blocks the transmission of nerve impulses in a specific area of the body, causing numbness and loss of sensation. Morphine is not a local anesthetic, but a systemic analgesic, which means it affects the whole body and reduces the perception of pain. Therefore, choice D is incorrect.
Choice area B
Choice A reason:
Mu receptors are one of the three types of opioid receptors in the body, along with kappa and delta receptors. Mu receptors are responsible for most of the analgesic and euphoric effects of opioids, as well as respiratory depression and physical dependence. Morphine has a high affinity for mu receptors and activates them strongly. Therefore, choice A is correct.
Choice B reason:
Kappa receptors are another type of opioid receptors in the body. Kappa receptors mediate some analgesic effects of opioids, as well as dysphoria, sedation, and miosis. Morphine has a low affinity for kappa receptors and activates them weakly. Therefore, choice B is incorrect.
Choice C reason:
Delta receptors are the third type of opioid receptors in the body. Delta receptors modulate some analgesic effects of opioids, as well as emotional responses and memory. Morphine has a low affinity for delta receptors and activates them weakly. Therefore, choice C is incorrect.
Choice D reason:
NMDA receptors are not opioid receptors, but glutamate receptors that are involved in synaptic plasticity, learning, memory, and pain modulation. Some drugs that act on NMDA receptors, such as ketamine and dextromethorphan, have analgesic properties, especially for neuropathic pain. Morphine does not act on NMDA receptors. Therefore, choice D is incorrect.
Choice E reason:
GABA receptors are not opioid receptors, but gamma-aminobutyric acid receptors that are involved in inhibitory neurotransmission in the central nervous system. Some drugs that act on GABA receptors, such as benzodiazepines and barbiturates, have sedative, anxiolytic, anticonvulsant, and muscle relaxant properties. Morphine does not act on GABA receptors. Therefore, choice E is incorrect.
Choice area C
Choice A reason:
Mild pain is pain that is easily tolerated and does not interfere with normal activities or sleep. Mild pain can usually be managed with non-opioid analgesics, such as acetaminophen or ibuprofen. Morphine is not used to relieve mild pain, as it is too potent and has more side effects and risks than non-opioid analgesics. Therefore, choice A is incorrect.
Choice B reason:
Moderate pain is pain that causes discomfort and affects normal activities or sleep to some extent. Moderate pain can usually be managed with combination analgesics, such as codeine or hydrocodone with acetaminophen or ibuprofen. Morphine can be used to relieve moderate pain in some cases, but it is not the first-line option, as it may be more effective and safer to use lower doses of opioids with non-opioid analgesics. Therefore, choice B is incorrect.
Choice C reason:
Severe pain is pain that causes significant distress and impairs normal activities or sleep to a great extent. Severe pain usually requires strong opioids, such as morphine or fentanyl, to achieve adequate relief. Morphine is commonly used to relieve severe pain in various settings, such as post-operative pain, cancer pain, or acute myocardial infarction. Therefore, choice C is correct.
Choice D reason:
Neuropathic pain is pain that results from damage or dysfunction of the nervous system, such as diabetic neuropathy or post-herpetic neuralgia. Neuropathic pain often responds poorly to conventional analgesics, including opioids. Morphine can be used to relieve neuropathic pain in some cases, but it may not be very effective or require higher doses than for nociceptive pain (pain that results from tissue damage or inflammation). Therefore, choice D is incorrect.
Choice E reason:
Inflammatory pain is pain that results from tissue damage or inflammation, such as arthritis or appendicitis. Inflammatory pain often responds well to non-opioid analgesics, especially NSAIDs, which have anti-inflammatory properties. Morphine can be used to relieve inflammatory pain in some cases, but it may not be necessary or optimal to use opioids for this type of pain, as they do not have anti-inflammatory effects and may cause more side effects and risks than non-opioid analgesics. Therefore, choice E is incorrect.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Apical pulse rate of 50 beats/minute requires nursing intervention prior to the administration of digoxin, which is a medication that slows down and strengthens the heartbeat. Digoxin can cause bradycardia, which is a slow heart rate below 60 beats/minute. Bradycardia can lead to inadequate blood flow and oxygen delivery to the body. The nurse should withhold the dose of digoxin and notify the prescriber if the apical pulse rate is below 60 beats/minute.
Choice B reason: Irregular apical pulse rhythm does not require nursing intervention prior to the administration of digoxin, which is a medication that treats arrhythmias, which are irregular heart rhythms. Digoxin can correct or prevent some types of arrhythmias, such as atrial fibrillation or flutter. The nurse should monitor the apical pulse rhythm and report any changes to the prescriber, but it is not a reason to withhold the dose of digoxin.
Choice C reason: Presence of a systolic heart murmur does not require nursing intervention prior to the administration of digoxin, which is a medication that improves the pumping function of the heart. A systolic heart murmur is a sound that occurs when the heart contracts and blood flows through a narrow or leaky valve. Digoxin can reduce the symptoms of heart failure, such as shortness of breath, fatigue, and edema, which may be associated with a systolic heart murmur. The nurse should document the presence and characteristics of the heart murmur, but it is not a reason to withhold the dose of digoxin.
Choice D reason: Apical pulse heard best at the pulmonic site does not require nursing intervention prior to the administration of digoxin, which is a medication that affects the electrical activity and contractility of the heart. The apical pulse is the heartbeat heard at the apex of the heart, which is located at the fifth intercostal space on the left midclavicular line. The pulmonic site is located at the second intercostal space on the left sternal border, where the sound of blood flow through the pulmonary valve can be heard. The nurse should listen to the apical pulse at the correct location, but it is not a reason to withhold the dose of digoxin.
Correct Answer is D
Explanation
Choice A reason: Promoting stomach emptying and preventing gastric reflux is not a relevant action of sevelamer, which is a phosphate binder that lowers serum phosphate levels in patients with CKD. Gastric reflux may be caused by other factors, such as hiatal hernia, obesity, or spicy foods.
Choice B reason: Buffering hydrochloric acid and preventing gastric erosion is not a pertinent action of sevelamer, which does not affect gastric acidity or mucosal integrity. Gastric erosion may be caused by other factors, such as NSAIDs, alcohol, or Helicobacter pylori infection.
Choice C reason: Preventing indigestion associated with ingestion of spicy foods is not a significant action of sevelamer, which does not affect digestion or food tolerance. Indigestion may be caused by other factors, such as overeating, stress, or gallstones.
Choice D reason: Binding with phosphorus in foods and preventing absorption is the correct action of sevelamer, which should be taken with meals to reduce the amount of phosphorus that enters the bloodstream from the diet. High serum phosphate levels can cause bone loss, calcification of soft tissues, and secondary hyperparathyroidism in patients with CKD.
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