Regular, long term use of laxatives may cause:
laxative dependence
stomach ulcers
reflux disease
laxative toxicity
The Correct Answer is A
A. laxative dependence: Chronic use of stimulant laxatives can lead to the bowel becoming reliant on external stimulation for defecation. Over time, this weakens natural peristalsis and results in need for progressively stronger doses or continued use to maintain bowel movements.
B. stomach ulcers: Stomach ulcers are typically caused by factors such as Helicobacter pylori infection or NSAID overuse. Laxatives do not erode the gastric lining or contribute to ulcer formation as part of their mechanism of action.
C. reflux disease: Gastroesophageal reflux disease (GERD) results from lower esophageal sphincter dysfunction and is unrelated to laxative use. Laxatives affect the colon and rectum, not the upper gastrointestinal structures involved in reflux.
D. laxative toxicity: While laxative abuse can lead to electrolyte imbalances, especially hypokalemia, "laxative toxicity" is not a widely recognized or specific medical condition. The main clinical concern is dependence, not toxicity per se.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. sucralfate: Sucralfate is a gastrointestinal protectant used to treat and prevent ulcers by forming a barrier over damaged mucosa. It does not affect the vomiting center or chemoreceptor trigger zone and has no antiemetic properties.
B. bisacodyl: Bisacodyl is a stimulant laxative used to treat constipation by increasing peristalsis and fluid accumulation in the colon. It is not used for nausea or vomiting and has no action on the central nervous system.
C. omeprazole: Omeprazole is a proton pump inhibitor that decreases gastric acid secretion. It is used to manage GERD and peptic ulcers but has no antiemetic effects or influence on the chemoreceptor trigger zone.
D. prochlorperazine: Prochlorperazine is a phenothiazine antiemetic that works by blocking dopamine receptors in the chemoreceptor trigger zone. It is frequently used to manage nausea, vomiting, and vertigo.
Correct Answer is C
Explanation
A. diazole oral: There is no widely used hypoglycemia treatment called "diazole."
B. glyburide oral: Glyburide is an oral hypoglycemic agent used to lower blood glucose in clients with type 2 diabetes. Administering it during a hypoglycemic crisis would worsen the condition by further reducing glucose levels.
C. glucagon intravenous injection: Glucagon stimulates glycogen breakdown in the liver, raising blood glucose levels rapidly. For a glucose level as low as 19 mg/dL, immediate IV administration is warranted when IV dextrose is unavailable or if rapid response is needed in an unconscious patient.
D. insulin subcutaneous injection: Insulin administration in a hypoglycemic patient would exacerbate the condition, potentially leading to seizures, coma, or death. Insulin is contraindicated in hypoglycemia and should never be given in such a situation.
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