When caring for a client who has been diagnosed with a peptic ulcer, the nurse administers omeprazole and amoxicillin. What diagnostic finding indicates therapeutic effects of this drug regimen?
a lack of dyspepsia
no gastroesophageal reflux
increased appetite and absence of nausea
absence of Helicobacter pylori
The Correct Answer is D
A. a lack of dyspepsia: While symptom relief is important, the primary therapeutic goal of the omeprazole and amoxicillin regimen is eradication of H. pylori. Dyspepsia can resolve temporarily with acid suppression alone and does not confirm that the underlying infection has been treated.
B. no gastroesophageal reflux: Omeprazole may help reduce reflux symptoms due to its acid-suppressing effects, but this is not a primary indicator of treatment success in peptic ulcer disease caused by H. pylori.
C. increased appetite and absence of nausea: Improved appetite and reduced nausea may occur as symptoms resolve, but they are nonspecific. These signs do not definitively confirm that H. pylori, the causative agent of many ulcers, has been successfully eradicated.
D. absence of Helicobacter pylori: The purpose of combining omeprazole (a proton pump inhibitor) with amoxicillin (an antibiotic) is to eliminate H. pylori. Confirming its absence through follow-up testing (e.g., urea breath test, stool antigen test) is the most reliable measure of therapeutic success.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["5"]
Explanation
Desired dose per administration = 20 mg.
- Determine the number of administrations in 24 hours.
"twice a day," which means 2 administrations in 24 hours.
- Calculate the total milligrams administered in 24 hours.
Total mg in 24 hours = 20 mg/dose × 2 doses/day
= 40 mg/day.
Available concentration = 40 mg/5 mL.
- Calculate the total milliliters to be given in 24 hours.
Volume (mL) = Total mg in 24 hours / (Available concentration (mg) / Available volume (mL))
= 40 mg / (40 mg / 5 mL)
= 40 mg / 8 mg/mL
= 5 mL.
Correct Answer is C
Explanation
A. antipeptic agent: Antipeptic agents, such as sucralfate, protect the ulcer site by forming a barrier over the lesion but do not reduce hydrochloric acid secretion. They provide symptomatic relief by shielding the stomach lining rather than altering acid production levels.
B. histamine-2 antagonist: H2-receptor antagonists like ranitidine or famotidine reduce acid secretion by blocking histamine receptors in the stomach lining. While effective, they are generally less potent than proton pump inhibitors in suppressing hydrochloric acid production
C. proton pump inhibitor: PPIs such as omeprazole or pantoprazole directly inhibit the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells. This action effectively blocks the final step in acid production, making them the most effective class for suppressing hydrochloric acid secretion.
D. prostaglandin: Prostaglandin analogs, like misoprostol, help protect the gastric mucosa by increasing mucus and bicarbonate production. They also mildly reduce acid secretion but are primarily used to prevent ulcers caused by NSAIDs rather than to suppress acid.
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