(Select all that apply): A client with MDD is prescribed an atypical antidepressant. Which statements are true about atypical antidepressants? (Select three).
They have the same mechanisms of action as SSRIs.
Bupropion blocks the reuptake of dopamine and norepinephrine.
Mirtazapine blocks serotonin and histamine receptors.
Trazodone blocks the reuptake of serotonin only.
They are associated with common side effects such as dry mouth and blurred vision.
Correct Answer : B,C,E
Choice B rationale:
Bupropion, an atypical antidepressant, indeed blocks the reuptake of both dopamine and norepinephrine. Unlike many other antidepressants, which primarily target serotonin, bupropion's mechanism of action involves increasing the levels of dopamine and norepinephrine in the brain.
Choice C rationale:
Mirtazapine, another atypical antidepressant, blocks serotonin and histamine receptors. By blocking histamine receptors, mirtazapine often leads to drowsiness, which can be a side effect of this medication.
Choice E rationale:
Atypical antidepressants are associated with common side effects such as dry mouth and blurred vision. These side effects are often due to their impact on various neurotransmitter systems, including histamine and acetylcholine. Choices A and D are incorrect because they misrepresent the mechanisms of atypical antidepressants.
Choice A rationale:
Choice A (They have the same mechanisms of action as SSRIs) is incorrect. Atypical antidepressants have different mechanisms of action compared to SSRIs. While SSRIs primarily target serotonin reuptake inhibition, atypical antidepressants like bupropion and mirtazapine have unique mechanisms involving other neurotransmitters.
Choice D rationale:
Choice D (Trazodone blocks the reuptake of serotonin only) is incorrect. Trazodone is an atypical antidepressant with a complex mechanism of action. It is an antagonist at certain serotonin receptors and inhibits serotonin reuptake, but it also has antagonistic effects on histamine receptors, which contribute to its sedative properties.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
Benzodiazepines can cause weight gain and increased appetite. Rationale: This statement is incorrect. Benzodiazepines are not typically associated with weight gain and increased appetite. Weight gain is more commonly associated with certain other psychotropic medications like some antipsychotics and mood stabilizers. Benzodiazepines primarily affect the central nervous system and are known for their sedative and anxiolytic properties rather than influencing appetite.
Choice B rationale:
Benzodiazepines are used to enhance the effects of dopamine in the brain. Rationale: This statement is incorrect. Benzodiazepines do not enhance the effects of dopamine in the brain. They work by enhancing the inhibitory effects of the neurotransmitter gamma-aminobutyric acid (GABA), which leads to sedative and calming effects. Dopamine is a separate neurotransmitter associated with reward, motivation, and movement control, and benzodiazepines do not directly influence its effects.
Choice C rationale:
Benzodiazepines are commonly prescribed as mood stabilizers. Rationale: This statement is incorrect. Benzodiazepines are not commonly prescribed as mood stabilizers. Mood stabilizers are a class of medications used to manage mood disorders like bipolar disorder. While benzodiazepines might be used in certain cases to manage anxiety or agitation associated with bipolar disorder, they are not considered primary mood stabilizers. Mood stabilizers like lithium, anticonvulsants (e.g., valproate, carbamazepine), and certain atypical antipsychotics are more commonly used for this purpose.
Choice D rationale:
Benzodiazepines may lead to cognitive impairment and dependence. Rationale: This statement is correct. Benzodiazepines are associated with potential cognitive impairment and the risk of dependence. These medications have sedative effects that can impact cognitive function, including memory and attention. Prolonged use of benzodiazepines can lead to physical and psychological dependence, making it important for healthcare providers to carefully assess and monitor their use in patients, particularly those with bipolar disorder.
.
Correct Answer is D
Explanation
Choice A rationale:
Dry mouth is a common side effect of many medications, but it is not a distinctive side effect of SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors). Dry mouth is more commonly associated with medications that affect salivary gland function, such as anticholinergic drugs.
Choice B rationale:
Weight loss can indeed be a side effect of SNRIs. These medications can impact appetite and metabolism, leading to weight loss in some individuals. However, it is not the most common or distinctive side effect when compared to other options.
Choice C rationale:
Constipation is a side effect that can occur with SNRIs, but it's not as prevalent or characteristic as some other side effects. Constipation is often associated with medications that have anticholinergic effects, which SNRIs generally have to a lesser extent.
Choice D rationale:
(Correct Choice) Insomnia is a well-known side effect of SNRIs. These medications can affect sleep patterns and may cause difficulties falling asleep or staying asleep. This side effect is particularly relevant to discuss with patients because it can impact their quality of life and overall well-being.
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