Serum sickness, which is a Type III Hypersensitivity Reaction, may occur in patients that have received which of the following medications?

Cephalosporin

Epinephrine

Diphenhydramine

Penicillin or Sulfonamide

Answer and Explanation

The Correct Answer is D

A.   Cephalosporin: Though cephalosporins can cause allergic reactions, they are less commonly associated with serum sickness compared to penicillins.
B.   Epinephrine: Epinephrine treats allergic reactions and does not cause serum sickness.
C.   Diphenhydramine: Diphenhydramine is an antihistamine used to alleviate hypersensitivity reactions.
D.   Penicillin or Sulfonamide: These medications are classic triggers for serum sickness, a delayed hypersensitivity reaction involving immune complex deposition.

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Correct Answer is C

Explanation

A. Obtain the client's vital signs: Although vital signs are essential, stopping the transfusion is the first priority to prevent further reaction.
B. Notify the charge nurse: Communication is important but not the immediate action.
C. Stop the transfusion: The first action is to stop the infusion to halt exposure to the potential allergen.
D. Administer prescribed diphenhydramine: Medication administration is secondary to stopping the transfusion.

A. Asian men B. Native American men C. Caucasian women D. African American women

Correct Answer is D

Explanation

A. Asian men: Asian populations have a lower risk compared to African American and Caucasian women.
B. Native American men: SLE is less common in Native American men than in women of other ethnic groups.
C. Caucasian women: While SLE is more common in women, African American women have a higher risk compared to Caucasian women.
D. African American women: African American women are at the highest risk for developing SLE, with more severe disease manifestations compared to other groups.

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Serum sickness, which is a Type III Hypersensitivity Reaction, may occur in patients that have received which of the following medications?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Correct Answer is C

Explanation

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Correct Answer is D

Explanation

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