The nurse has been teaching the caregiver about Aricept. The nurse knows teaching has been effective by which of the following statements?
Let's hope this medication will stop the Alzheimer's disease from progressing any further
It is important to take this medication on an empty stomach
I'll be eager to see if this medication makes any improvement in concentration
This medication will slow the progress of Alzheimer's disease temporarily
The Correct Answer is D
Choice A reason: Aricept (donepezil) is a cholinesterase inhibitor that increases acetylcholine levels in the brain, temporarily improving cognitive symptoms in Alzheimer’s disease. It does not stop disease progression, as Alzheimer’s involves progressive neuronal loss due to amyloid plaques and tau tangles. This statement is scientifically inaccurate, as no medication halts Alzheimer’s neurodegenerative process.
Choice B reason: Taking Aricept on an empty stomach is not required, as it can be taken with or without food. Its absorption is not significantly affected by food, as it is metabolized hepatically via CYP2D6 and CYP3A4. This statement is incorrect, as it misrepresents the administration guidelines, potentially causing unnecessary restrictions for the patient.
Choice C reason: While Aricept may improve concentration by enhancing cholinergic activity in Alzheimer’s, this statement focuses on expectation rather than understanding its therapeutic role. It does not address the drug’s primary effect of temporarily slowing cognitive decline. Concentration improvement is a secondary benefit, not the primary mechanism, making this less precise scientifically.
Choice D reason: Aricept temporarily slows Alzheimer’s disease progression by inhibiting acetylcholinesterase, increasing acetylcholine, and supporting cognitive function in mild to moderate cases. It does not cure or stop the disease, as neuronal degeneration continues due to amyloid and tau pathology. This statement accurately reflects the drug’s mechanism and temporary symptomatic relief, aligning with clinical evidence.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Reminding a dementia patient of forgotten information supports memory function and reduces frustration. Dementia involves progressive neuronal loss, impairing short-term memory due to hippocampal and cortical damage. Gentle reminders align with cognitive support strategies, maintaining patient comfort without overwhelming their limited cognitive capacity, making this approach appropriate.
Choice B reason: Engaging in favorite activities leverages preserved long-term memory in dementia, as the disease primarily affects short-term memory and executive function due to amyloid plaques and tau tangles. Familiar tasks reduce agitation and promote well-being, as they align with the patient’s cognitive abilities, making this a scientifically sound caregiving strategy.
Choice C reason: Introducing new and different activities daily is inappropriate, as dementia patients struggle with learning and adapting due to impaired neuroplasticity and hippocampal dysfunction. Novel tasks can cause confusion and agitation, as they overwhelm cognitive reserves. Familiar routines are more effective, requiring intervention to educate the caregiver on maintaining consistency.
Choice D reason: Encouraging discussion about friends and family taps into preserved long-term memory in early dementia, as the disease initially spares autobiographical memory. Social engagement supports emotional well-being and cognitive stimulation, reducing isolation. This approach is scientifically appropriate, as it aligns with the patient’s cognitive strengths and promotes quality of life.
Correct Answer is C
Explanation
Choice A reason: Disturbed Sensory Perception involves altered sensory processing, like hallucinations, not specific to anxiety disorders with flashbacks or hypervigilance. These symptoms stem from heightened amygdala activity and dysregulated cortisol in trauma-related disorders, not sensory distortion. This diagnosis is less precise, as it does not capture the trauma-specific psychological and autonomic responses observed.
Choice B reason: Anxiety is a broad diagnosis encompassing excessive worry and autonomic arousal, but it is less specific than Post-Trauma Syndrome for symptoms like flashbacks and numbing. These indicate a trauma-related disorder, likely PTSD, driven by amygdala hyperactivation and HPA axis dysregulation, requiring a diagnosis that addresses the traumatic etiology and specific symptoms.
Choice C reason: Post-Trauma Syndrome, aligned with PTSD, is the most appropriate diagnosis for symptoms like flashbacks, hypervigilance, and numbing, which result from trauma-induced changes in the amygdala, hippocampus, and prefrontal cortex. These cause intrusive memories, heightened arousal, and emotional detachment, accurately reflecting the neurobiological impact of trauma on stress response systems.
Choice D reason: Powerlessness reflects perceived lack of control, not specific to flashbacks or hypervigilance. While trauma can cause feelings of helplessness, the defining symptoms here involve trauma-specific neurological changes, like amygdala hyperactivity, better captured by Post-Trauma Syndrome. Powerlessness is secondary and l
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