The nurse has been teaching the caregiver about Aricept. The nurse knows teaching has been effective by which of the following statements?
Let's hope this medication will stop the Alzheimer's disease from progressing any further
It is important to take this medication on an empty stomach
I'll be eager to see if this medication makes any improvement in concentration
This medication will slow the progress of Alzheimer's disease temporarily
The Correct Answer is D
Choice A reason: Aricept (donepezil) is a cholinesterase inhibitor that increases acetylcholine levels in the brain, temporarily improving cognitive symptoms in Alzheimer’s disease. It does not stop disease progression, as Alzheimer’s involves progressive neuronal loss due to amyloid plaques and tau tangles. This statement is scientifically inaccurate, as no medication halts Alzheimer’s neurodegenerative process.
Choice B reason: Taking Aricept on an empty stomach is not required, as it can be taken with or without food. Its absorption is not significantly affected by food, as it is metabolized hepatically via CYP2D6 and CYP3A4. This statement is incorrect, as it misrepresents the administration guidelines, potentially causing unnecessary restrictions for the patient.
Choice C reason: While Aricept may improve concentration by enhancing cholinergic activity in Alzheimer’s, this statement focuses on expectation rather than understanding its therapeutic role. It does not address the drug’s primary effect of temporarily slowing cognitive decline. Concentration improvement is a secondary benefit, not the primary mechanism, making this less precise scientifically.
Choice D reason: Aricept temporarily slows Alzheimer’s disease progression by inhibiting acetylcholinesterase, increasing acetylcholine, and supporting cognitive function in mild to moderate cases. It does not cure or stop the disease, as neuronal degeneration continues due to amyloid and tau pathology. This statement accurately reflects the drug’s mechanism and temporary symptomatic relief, aligning with clinical evidence.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Monitoring vital signs is critical in withdrawal delirium, as it is a medical emergency involving autonomic hyperactivity from alcohol or drug cessation. Dehydration and electrolyte imbalances elevate heart rate and blood pressure, risking seizures or cardiovascular collapse. Regular monitoring detects instability early, guiding fluid replacement and medication to stabilize cerebral and systemic function.
Choice B reason: Keeping the room dark may reduce sensory overload in withdrawal delirium, but it does not address physiologic instability like dehydration or autonomic hyperactivity. Darkness may calm agitation but risks disorientation in a confused patient, as visual cues aid reality testing. This choice is less critical than monitoring vital signs for ensuring systemic stability.
Choice C reason: Withholding oral fluids is contraindicated in withdrawal delirium, as dehydration exacerbates symptoms like confusion and autonomic instability. Fluid loss from sweating or vomiting, common in withdrawal, disrupts electrolyte balance and cerebral perfusion. Providing fluids corrects hypovolemia, making this choice scientifically inappropriate for maintaining physiologic stability in this critical condition.
Choice D reason: Applying ice to the tongue may reduce swelling from trauma, but it does not address the systemic instability of withdrawal delirium, such as dehydration or autonomic hyperactivity. Tongue swelling is a secondary issue compared to life-threatening risks like seizures or arrhythmias, which require monitoring vital signs and fluid management for stabilization.
Correct Answer is D
Explanation
Choice A reason: Orientation to person but disorientation to place and time occurs in both delirium and dementia. In delirium, acute cerebral dysfunction from causes like infection disrupts attention, while dementia’s gradual hippocampal loss affects memory. This symptom is non-specific, as it does not distinguish the acute onset critical to delirium diagnosis.
Choice B reason: Fragmented, incoherent speech can occur in delirium due to acute brain dysfunction or in advanced dementia from cortical degeneration. It reflects disrupted neural communication but is not specific to delirium’s rapid onset. This symptom alone does not differentiate the conditions, as both involve cognitive processing deficits.
Choice C reason: A history of increasing confusion over years indicates dementia, characterized by progressive neuronal loss, particularly in Alzheimer’s or vascular dementia. Delirium, conversely, has an acute onset due to reversible causes like infection. This chronic history rules out delirium, making this choice incorrect for identifying delirium.
Choice D reason: Being oriented and alert on admission, then developing confusion, indicates delirium’s acute onset, typically from pneumonia-related hypoxia or sepsis disrupting cerebral metabolism. Unlike dementia’s gradual progression, delirium’s rapid cognitive decline, often within days, reflects reversible brain dysfunction, making this the key differentiator in diagnosis.
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