The nurse has been teaching the caregiver about Aricept. The nurse knows teaching has been effective by which of the following statements?
Let's hope this medication will stop the Alzheimer's disease from progressing any further
It is important to take this medication on an empty stomach
I'll be eager to see if this medication makes any improvement in concentration
This medication will slow the progress of Alzheimer's disease temporarily
The Correct Answer is D
Choice A reason: Aricept (donepezil) is a cholinesterase inhibitor that increases acetylcholine levels in the brain, temporarily improving cognitive symptoms in Alzheimer’s disease. It does not stop disease progression, as Alzheimer’s involves progressive neuronal loss due to amyloid plaques and tau tangles. This statement is scientifically inaccurate, as no medication halts Alzheimer’s neurodegenerative process.
Choice B reason: Taking Aricept on an empty stomach is not required, as it can be taken with or without food. Its absorption is not significantly affected by food, as it is metabolized hepatically via CYP2D6 and CYP3A4. This statement is incorrect, as it misrepresents the administration guidelines, potentially causing unnecessary restrictions for the patient.
Choice C reason: While Aricept may improve concentration by enhancing cholinergic activity in Alzheimer’s, this statement focuses on expectation rather than understanding its therapeutic role. It does not address the drug’s primary effect of temporarily slowing cognitive decline. Concentration improvement is a secondary benefit, not the primary mechanism, making this less precise scientifically.
Choice D reason: Aricept temporarily slows Alzheimer’s disease progression by inhibiting acetylcholinesterase, increasing acetylcholine, and supporting cognitive function in mild to moderate cases. It does not cure or stop the disease, as neuronal degeneration continues due to amyloid and tau pathology. This statement accurately reflects the drug’s mechanism and temporary symptomatic relief, aligning with clinical evidence.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Reminding a dementia patient of forgotten information supports memory function and reduces frustration. Dementia involves progressive neuronal loss, impairing short-term memory due to hippocampal and cortical damage. Gentle reminders align with cognitive support strategies, maintaining patient comfort without overwhelming their limited cognitive capacity, making this approach appropriate.
Choice B reason: Engaging in favorite activities leverages preserved long-term memory in dementia, as the disease primarily affects short-term memory and executive function due to amyloid plaques and tau tangles. Familiar tasks reduce agitation and promote well-being, as they align with the patient’s cognitive abilities, making this a scientifically sound caregiving strategy.
Choice C reason: Introducing new and different activities daily is inappropriate, as dementia patients struggle with learning and adapting due to impaired neuroplasticity and hippocampal dysfunction. Novel tasks can cause confusion and agitation, as they overwhelm cognitive reserves. Familiar routines are more effective, requiring intervention to educate the caregiver on maintaining consistency.
Choice D reason: Encouraging discussion about friends and family taps into preserved long-term memory in early dementia, as the disease initially spares autobiographical memory. Social engagement supports emotional well-being and cognitive stimulation, reducing isolation. This approach is scientifically appropriate, as it aligns with the patient’s cognitive strengths and promotes quality of life.
Correct Answer is D
Explanation
Choice A reason: Expecting dementia clients to consistently ask for needed items is incorrect, as short-term memory loss from hippocampal degeneration impairs their ability to articulate needs. Cognitive deterioration disrupts executive function and communication, making this assumption inaccurate and reflecting a misunderstanding of dementia’s neurobiological impact on memory and expression.
Choice B reason: Assuming ambulatory dementia clients can independently perform activities of daily living is incorrect. Dementia’s progressive neuronal loss, particularly in the cortex and hippocampus, impairs planning and execution of tasks like dressing or hygiene, despite physical mobility. This reflects a misunderstanding of cognitive versus motor function in dementia’s pathology.
Choice C reason: Expecting dementia clients to know meal times is incorrect, as temporal disorientation from hippocampal and prefrontal cortex damage impairs memory and time perception. Cognitive deterioration disrupts routine recall, making this assumption inaccurate. It fails to recognize the neurobiological basis of memory deficits central to dementia’s progression.
Choice D reason: Not recognizing family is a common dementia symptom, as long-term memory impairment from cortical and hippocampal neurodegeneration disrupts autobiographical memory. This reflects accurate understanding of dementia’s progressive impact on memory systems, where familiar faces become unrecognizable, aligning with the disease’s neurobiological effects on recognition and recall.
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