The nurse is caring for a client with lupus and is reviewing the medication list. Which of the following prescriptions would not correlate to this illness?
Donepezil
Prednisone
Hydroxychloroquine
Methotrexate
The Correct Answer is A
Choice A reason: Donepezil treats Alzheimer’s by inhibiting cholinesterase, boosting acetylcholine for cognition. Lupus, an autoimmune disease, doesn’t involve dementia primarily, so this drug lacks relevance to its management.
Choice B reason: Prednisone, a corticosteroid, suppresses inflammation and immune response in lupus, reducing joint pain and organ damage from autoantibody activity, making it a standard treatment.
Choice C reason: Hydroxychloroquine modulates immunity and reduces lupus flares by stabilizing lysosomes and decreasing autoantibody production, directly addressing its autoimmune pathology.
Choice D reason: Methotrexate, an immunosuppressant, inhibits folate metabolism, curbing immune cell proliferation in lupus, effectively managing severe symptoms like arthritis or organ involvement.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: ESRD impairs fluid excretion, causing hypervolemia, leading to edema, crackles from pulmonary fluid, and hypertension from increased vascular volume, matching these symptoms.
Choice B reason: Hypovolemia, low fluid volume, causes hypotension and dry tissues, not swelling, crackles, or high blood pressure, which indicate excess fluid, not deficit.
Choice C reason: Hyperkalemia elevates potassium, causing arrhythmias or muscle issues, not directly linked to crackles, edema, or hypertension, which are fluid-related in ESRD.
Choice D reason: Hyponatremia, low sodium, may cause neurological symptoms, but crackles, edema, and hypertension point to fluid overload, not sodium imbalance primarily.
Correct Answer is C
Explanation
Choice A reason: Crackles indicate pulmonary edema from left-sided heart failure, where fluid backs up into lungs, not right-sided failure, which affects systemic circulation instead.
Choice B reason: Orthopnea, dyspnea when lying flat, results from left-sided failure’s pulmonary congestion, not right-sided failure, which causes systemic venous pooling, not lung issues.
Choice C reason: Jugular venous distention occurs in right-sided heart failure as the right ventricle fails, backing blood into veins, elevating neck vein pressure visibly.
Choice D reason: Blood-tinged sputum suggests pulmonary edema or infarction, tied to left-sided failure or embolism, not right-sided failure’s systemic congestion pattern.
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