The nurse is caring for a patient who has a new prescription for levothyroxine.
The nurse will include in the teaching plan that levothyroxine decreases the action of which medication?
Metformin.
Warfarin.
Sertraline.
Methylprednisolone.
The Correct Answer is B
Choice A rationale
Metformin is used to manage diabetes, primarily by improving insulin sensitivity and reducing glucose production in the liver. Levothyroxine, used to treat hypothyroidism, does not significantly impact the action of metformin. The two medications do not have a direct interaction that decreases metformin's efficacy.
Choice B rationale
Levothyroxine can decrease the action of warfarin by increasing the metabolism of clotting factors in the liver, which may reduce the anticoagulant effect of warfarin. This interaction necessitates closer monitoring of INR (International Normalized Ratio) levels and potential dose adjustments of warfarin to maintain its therapeutic effect.
Choice C rationale
Sertraline is an antidepressant that belongs to the selective serotonin reuptake inhibitor (SSRI) class. While it can interact with other medications, levothyroxine does not significantly decrease its action. Therefore, no major adjustments are needed when both drugs are prescribed together.
Choice D rationale
Methylprednisolone, a corticosteroid, is used for its anti-inflammatory and immunosuppressant properties. Levothyroxine does not decrease the action of methylprednisolone. These medications do not have a significant pharmacological interaction that would require adjusting methylprednisolone’s dosage.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Prevent graft versus host disease (GVHD) is a common complication following an allogeneic stem cell transplant. Immunosuppressant medications are given to prevent the donor immune cells from attacking the recipient's body tissues, which is GVHD. This prevention is crucial for the success of the transplant and the patient's overall recovery.
Choice B rationale
Prevent graft rejection is more commonly associated with solid organ transplants like kidney or liver transplants. In the context of stem cell transplants, preventing GVHD is the primary concern rather than preventing graft rejection.
Choice C rationale
Preventing hospital-acquired infections is important for all patients, especially those with compromised immune systems. However, this is not the primary indication for immunosuppressant medications following an allogeneic stem cell transplant. Other measures, such as infection control protocols, are more directly related to this.
Choice D rationale
Preventing a relapse of leukemia is a key goal of the overall treatment plan for leukemia patients. However, immunosuppressant medications do not directly prevent a relapse; instead, they help manage complications like GVHD that can arise from the transplant process.
Correct Answer is A
Explanation
Choice A rationale
Hypercalcemia is common in patients with bone metastasis. Symptoms include weakness, fatigue, confusion, and excessive thirst. The nurse should notify the provider and draw blood to obtain the ionized calcium level for proper diagnosis and treatment.
Choice B rationale
Tumor lysis syndrome typically occurs in patients with rapidly proliferating tumors undergoing treatment, leading to the release of intracellular contents. Symptoms include hyperuricemia, not excessive thirst. This choice does not match the patient's presentation.
Choice C rationale
While infection can cause weakness and confusion, it does not typically cause extreme thirst. The patient's symptoms are more indicative of hypercalcemia, making this choice less relevant.
Choice D rationale
Bleeding can cause weakness and confusion due to anemia, but it does not cause extreme thirst. The symptoms of the patient are more aligned with hypercalcemia than bleeding.
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