The nurse is explaining to a patient why oral antihyperglycemic agents are not effective in Type 1 diabetes. What is the reason?
People with Type 1 diabetes have little or none of their own insulin that can be released.
People with Type 1 diabetes would need so much of an oral antihyperglycemic agent that it would cost too much.
People with Type 1 diabetes have resistance to their endogenous insulin.
People with Type 1 diabetes would have more episodes of hypoglycemia with oral antihyperglycemic agents.
The Correct Answer is A
Choice A rationale
People with Type 1 diabetes have little or no insulin that can be released. This is because their pancreatic β-cells, which produce insulin, are destroyed by an autoimmune process. Without insulin, glucose cannot be taken up into cells to be used for energy. Oral antihyperglycemic agents work by increasing the release of insulin or increasing the body’s sensitivity to insulin, so they are not effective in Type 1 diabetes where there is an absolute insulin deficiency.
Choice B rationale
The cost of oral antihyperglycemic agents is not the primary reason they are not used in Type 1 diabetes. The main issue is the lack of insulin production, which these medications cannot address.
Choice C rationale
People with Type 1 diabetes do not typically have resistance to their endogenous insulin. Insulin resistance is more commonly associated with Type 2 diabetes.
Choice D rationale
While hypoglycemia can occur with the use of some antihyperglycemic agents, this is not the primary reason these medications are not used in Type 1 diabetes. The main issue is the absolute deficiency of insulin.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
While understanding the recommended diabetic diet is important for managing type 1 diabetes, it is not the immediate priority for a client who has received no instruction on diabetes management. Without insulin, a person with type 1 diabetes can develop life- threatening diabetic ketoacidosis, regardless of their diet.
Choice B rationale
Administration of insulin is the immediate priority for a client newly diagnosed with type 1 diabetes. In type 1 diabetes, the body does not produce insulin, a hormone that regulates blood sugar levels. Without insulin, blood sugar levels can become dangerously high, leading to diabetic ketoacidosis, a serious condition that requires emergency medical treatment.
Choice C rationale
While exercise is an important part of managing diabetes, it is not the immediate priority for a client newly diagnosed with type 1 diabetes who has received no instruction on diabetes management. Exercise can help regulate blood sugar levels, but without insulin, exercise alone is not sufficient to prevent diabetic ketoacidosis.
Choice D rationale
Urine testing for ketones is an important part of managing type 1 diabetes, especially during illness or stress, when ketone levels can rise quickly. However, it is not the immediate priority for a client newly diagnosed with type 1 diabetes who has received no instruction on diabetes management.
Correct Answer is B
Explanation
Choice A rationale
Febrile and shallow respirations are not typically associated with uncontrolled diabetes mellitus and ketoacidosis. These symptoms could be indicative of a different medical condition.
Choice B rationale
An increased rate and depth of respiration, also known as Kussmaul breathing, is a common clinical manifestation in patients with uncontrolled diabetes mellitus and ketoacidosis.
Choice C rationale
Weakness and weight gain are not typically associated with uncontrolled diabetes mellitus and ketoacidosis. These symptoms could be indicative of a different medical condition.
Choice D rationale
Extremity tremors followed by seizure activity are not typically associated with uncontrolled diabetes mellitus and ketoacidosis. These symptoms could be indicative of a different medical condition.
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