The nurse is providing an in-service on non-steroidal anti-inflammatory drugs (NSAIDs). Which of the following medications is a first-generation NSAID that inhibits both COX-1 and COX-2 enzymes?
Celecoxib Celebrex
Morphine sulfate (Astramorph)
Metformin (Glucophage)
Ibuprofen (Motrin)
The Correct Answer is D
Rationale
A. Celecoxib is a second-generation NSAID that specifically inhibits COX-2 enzymes and is less likely to cause gastrointestinal side effects compared to first-generation NSAIDs.
B. Morphine sulfate is an opioid analgesic and does not have NSAID properties. It works by binding to opioid receptors to relieve pain.
C. Metformin is an oral medication used to manage blood glucose in type 2 diabetes and is not an NSAID.
D. Ibuprofen is a first-generation NSAID that inhibits both COX-1 and COX-2 enzymes, reducing pain, inflammation, and fever.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","C","D"]
Explanation
A. Priapism is a rare side effect that can occur with certain medications, but it is not commonly associated with cimetidine.
B. Cimetidine, a H2 blocker used for stomach acid reduction, can cause decreased libido as a side effect, especially in long-term use, due to its antiandrogenic properties.
C. Sedation is a potential side effect of cimetidine, as it can cross the blood-brain barrier and cause central nervous system effects such as drowsiness.
D. Impotence is another side effect of cimetidine, due to its antiandrogenic effects.
Correct Answer is C
Explanation
A. Nausea is a common symptom of the condition being treated with prochlorperazine (such as nausea from chemotherapy), but it is not a complication of the medication itself.
B. Anxiety is not a common complication of prochlorperazine. It is a dopamine antagonist, and while it may cause sedation, it is not known for causing anxiety.
C. Prochlorperazine is associated with cardiac side effects such as a prolonged QT interval, which can lead to arrhythmias. This is a serious complication and requires monitoring.
D. Vomiting is not a typical side effect of prochlorperazine; in fact, prochlorperazine is used to prevent nausea and vomiting.
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