The nurse is teaching nursing students about the concept of medications’ half-life. The nurse asks students: If we administer 10 mg of medication X, which has a half-life of one day, to the patient, how much medication will remain in the patient’s body after three days?
0 mg, the medication will be out of the patient’s body.
1.25 mg.
5 mg.
1 mg.
The Correct Answer is B
Choice A Reason:
The statement that the medication will be completely out of the patient’s body after three days is incorrect. The half-life of a drug indicates the time it takes for the concentration of the drug in the body to reduce by half. After one half-life (one day), 50% of the drug remains. After two half-lives (two days), 25% remains. After three half-lives (three days), 12.5% remains. Therefore, some amount of the drug will still be present in the body after three days.
Choice B Reason:
To calculate the amount of medication remaining after three days, we use the half-life formula. Starting with 10 mg, after one day (one half-life), 5 mg remains. After two days (two half-lives), 2.5 mg remains. After three days (three half-lives), 1.25 mg remains. This calculation shows that 1.25 mg of the medication will still be in the patient’s body after three days.
Choice C Reason:
The choice of 5 mg is incorrect because it represents the amount of medication remaining after one half-life (one day), not three half-lives. After one day, 50% of the initial dose remains, which is 5 mg. However, the question asks for the amount remaining after three days.
Choice D Reason:
The choice of 1 mg is also incorrect. After three half-lives, the amount of medication remaining is 12.5% of the initial dose. For an initial dose of 10 mg, this would be 1.25 mg, not 1 mg. The calculation must accurately reflect the reduction by half for each half-life period.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A Reason:
Fat necrosis occurs when fatty tissues are damaged, leading to the release of enzymes that break down fat cells. This type of necrosis is commonly seen in the pancreas and breast tissue, often due to trauma or pancreatitis. It is not typically associated with brain tissue.
Choice B Reason:
Coagulative necrosis is characterized by the preservation of the basic outline of the coagulated cells for a few days after cell death. This type of necrosis is usually seen in tissues affected by ischemia, such as the heart, kidneys, and adrenal glands. However, it is not the typical pattern of necrosis seen in brain tissue.
Choice C Reason:
Caseous necrosis is a form of cell death in which the tissue maintains a cheese-like appearance. It is most commonly associated with tuberculosis infections in the lungs. This type of necrosis is not typically seen in brain tissue.
Choice D Reason:
Liquefactive necrosis is the correct answer. This type of necrosis occurs when the tissue becomes soft and liquefied, often forming a pus-filled cavity. It is commonly seen in the brain due to ischemic injury or bacterial infections. The high lipid content and low structural support in brain tissue make it particularly susceptible to liquefactive necrosis.
Correct Answer is D
Explanation
Choice A Reason:
Beta2 activation results in bronchodilation. This is a well-known effect where the activation of beta2 adrenergic receptors in the smooth muscle of the airways leads to relaxation and widening of the airways, making it easier to breathe. This effect is commonly utilized in the treatment of asthma and other respiratory conditions.
Choice B Reason:
Beta2 activation also results in glycogenolysis. This process involves the breakdown of glycogen into glucose, which increases blood sugar levels. This effect is part of the body’s response to stress, providing additional energy for the “fight or flight” response.
Choice C Reason:
Beta2 activation results in vasodilation of skeletal muscles. This means that the blood vessels supplying the skeletal muscles widen, increasing blood flow to these muscles. This effect helps to deliver more oxygen and nutrients to the muscles during periods of increased activity.
Choice D Reason:
This is the correct answer. Beta2 activation does not result in the contraction of uterine muscle; rather, it causes relaxation of the uterine smooth muscle. This effect is beneficial in preventing premature labor by reducing uterine contractions. Therefore, the statement that beta2 activation results in contraction of uterine muscle is incorrect and indicates a need for further teaching.
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