The nurse is teaching nursing students about the concept of medications’ half-life. The nurse asks students: If we administer 10 mg of medication X, which has a half-life of one day, to the patient, how much medication will remain in the patient’s body after three days?
0 mg, the medication will be out of the patient’s body.
1.25 mg.
5 mg.
1 mg.
The Correct Answer is B
Choice A Reason:
The statement that the medication will be completely out of the patient’s body after three days is incorrect. The half-life of a drug indicates the time it takes for the concentration of the drug in the body to reduce by half. After one half-life (one day), 50% of the drug remains. After two half-lives (two days), 25% remains. After three half-lives (three days), 12.5% remains. Therefore, some amount of the drug will still be present in the body after three days.
Choice B Reason:
To calculate the amount of medication remaining after three days, we use the half-life formula. Starting with 10 mg, after one day (one half-life), 5 mg remains. After two days (two half-lives), 2.5 mg remains. After three days (three half-lives), 1.25 mg remains. This calculation shows that 1.25 mg of the medication will still be in the patient’s body after three days.
Choice C Reason:
The choice of 5 mg is incorrect because it represents the amount of medication remaining after one half-life (one day), not three half-lives. After one day, 50% of the initial dose remains, which is 5 mg. However, the question asks for the amount remaining after three days.
Choice D Reason:
The choice of 1 mg is also incorrect. After three half-lives, the amount of medication remaining is 12.5% of the initial dose. For an initial dose of 10 mg, this would be 1.25 mg, not 1 mg. The calculation must accurately reflect the reduction by half for each half-life period.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A Reason:
The exhaustion stage is the final phase of the general adaptation syndrome (GAS). It occurs when the body has been exposed to stress for a prolonged period and can no longer maintain resistance. Symptoms of exhaustion include fatigue, burnout, depression, and decreased stress tolerance. Since the student is experiencing an immediate response to a sudden stressor, this stage does not apply.
Choice B Reason:
Adaptation is not a specific stage in the general adaptation syndrome. The correct stages are alarm, resistance, and exhaustion. Therefore, this choice is incorrect.
Choice C Reason:
This is the correct answer. The alarm stage is the initial phase of the general adaptation syndrome, also known as the “fight-or-flight” response. During this stage, the body reacts to a stressor by activating the sympathetic nervous system, which leads to increased heart rate, rapid breathing, and heightened alertness. The student’s reaction to the near-miss accident fits this description perfectly.
Choice D Reason:
The stage of resistance is the second phase of the general adaptation syndrome. During this stage, the body attempts to adapt to the stressor and return to a state of balance. If the stressor persists, the body remains on high alert, but the initial shock of the alarm stage has passed. Since the student’s response is immediate and acute, it aligns with the alarm stage rather than the resistance stage.
Correct Answer is A
Explanation
Choice A Reason:
Necrosis is the term used to describe the death of cells or tissues through injury or disease, particularly when it involves severe cell swelling, breakdown of organelles, and release of cellular debris. This process is typically uncontrolled and results from factors such as lack of blood flow (ischemia), toxins, or trauma. In the context of a heart attack, necrosis occurs due to the lack of oxygen and nutrients, leading to cell death and tissue damage.
Choice B Reason:
Apoptosis is a form of programmed cell death that occurs in a controlled and regulated manner. It is a natural process that helps maintain homeostasis by eliminating damaged or unnecessary cells without causing inflammation. Unlike necrosis, apoptosis involves cell shrinkage, chromatin condensation, and DNA fragmentation, but it does not result in the release of cellular debris.
Choice C Reason:
Adaptation refers to the changes that cells undergo in response to stress or adverse conditions to survive and maintain function. These changes can include hypertrophy, hyperplasia, atrophy, and metaplasia. Adaptation is a reversible process and does not involve cell death or the breakdown of cellular components.
Choice D Reason:
Pathologic calcification is the abnormal deposition of calcium salts in tissues. It can occur in areas of necrosis (dystrophic calcification) or in normal tissues due to hypercalcemia (metastatic calcification). While pathologic calcification can be associated with cell injury and death, it is not the primary process described in the scenario of a heart attack leading to cell death with severe swelling and breakdown of organelles.
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