The nurse receives the following order: "Ferrous sulfate 325 mg four times a day PO. Give on empty stomach." Even before researching, the nurse guesses that this is because the medication:
is better absorbed when there is no food in the stomach.
is destroyed by acid in the stomach
can cause constipation
is irritating to the gastric mucosa and may cause bleeding
The Correct Answer is B
Choice A rationale: Iron absorption is influenced by several factors, including the presence of food in the stomach. Food can interfere with iron absorption by forming
insoluble complexes with iron, reducing its bioavailability. Therefore, ferrous sulfate should be taken on an empty stomach, preferably one hour before or two hours after meals, to enhance its absorption and effectiveness.
Choice B rationale: Ferrous sulfate is not destroyed by acid in the stomach but instead acid enhances iron absorption by keeping it in a soluble form.
Choice C rationale: Constipation is a common side effect of iron supplementation, but this is not the primary reason for taking it on an empty stomach.
Choice D rationale: Ferrous sulfate can cause gastrointestinal bleeding in some cases, but this is not the primary reason for taking it on an empty stomach.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale: Applying an ice pack after a topical agent is not primarily for decreasing discomfort but rather to achieve a specific therapeutic effect.
Choice B rationale: Applying an ice pack can slow the absorption of the topical drug, allowing for prolonged local action.
Choice C rationale: Enhancing drug excretion is not typically achieved by applying an ice pack.
Choice D rationale: Maximizing drug distribution is not the primary purpose of applying an ice pack after a topical agent.
Correct Answer is ["B","D","E"]
Explanation
Choice A rationale: Acetaminophen 500 mg PO is subject to the first pass effect as it is absorbed through the gastrointestinal system.
Choice B rationale: Dulcolax suppository is not subject to the first pass effect as it is administered rectally.
Choice C rationale: Aspirin 10 mg PO is subject to the first pass effect as it is absorbed through the gastrointestinal system.
Choice D rationale: Fentanyl 25 mcg/h via transdermal patch avoids the first pass effect as it is absorbed through the skin.
Choice E rationale: Morphine 0.4 mg IV avoids the first pass effect as it is administered intravenously.
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