The practical nurse (PN) administers filgrastim subcutaneous to a client with neutropenia. The client becomes troubled with bone pain. Which action should the PN take?

Choice A reason: Montelukast is a leukotriene receptor antagonist that inhibits leukotrienes, mediators of inflammation in allergic responses. By blocking these, it reduces airway inflammation, bronchoconstriction, and mucus production, preventing asthma or allergic rhinitis symptoms. This prophylactic action targets the immune response to allergens, stabilizing respiratory function before symptoms escalate.

Choice B reason: Montelukast does not increase mucus production. Instead, it reduces mucus by inhibiting leukotriene-driven inflammation in the airways. Increased mucus is a symptom of uncontrolled asthma or allergies, which montelukast aims to prevent. This choice is incorrect as it contradicts the drug’s mechanism of reducing inflammatory responses in the lungs.

Choice C reason: Montelukast does not contract respiratory smooth muscles. It prevents bronchoconstriction by blocking leukotrienes, which cause smooth muscle contraction in asthma. By inhibiting this pathway, it promotes airway relaxation, not contraction. This choice is incorrect, as it misrepresents the drug’s role in maintaining open airways.

Choice D reason: Montelukast does not repair damaged lung tissue. Its primary role is to prevent inflammation and bronchoconstriction caused by allergens. Lung tissue repair involves other physiological processes, not influenced by montelukast. This choice is incorrect, as it falsely attributes tissue regeneration to a drug focused on immune modulation.

Choice A reason: Tetracycline causes photosensitivity, increasing UV-induced skin damage risk due to its accumulation in skin cells, triggering photochemical reactions. Protecting skin with sunblock or clothing prevents severe sunburn or rash, making this critical instruction for safe use during chlamydia treatment.

Choice B reason: Taking tetracycline with meals or milk reduces absorption, as calcium and magnesium bind the drug, forming insoluble complexes. This decreases efficacy, making it incorrect. Tetracycline should be taken on an empty stomach to ensure optimal bioavailability for infection treatment.

Choice C reason: Grapefruit juice affects drugs metabolized by CYP3A4, not tetracycline, which is not significantly influenced by this enzyme. This instruction is irrelevant, as tetracycline’s pharmacokinetics are unaffected by grapefruit, making it unnecessary for managing chlamydia treatment.

Choice D reason: Wearing tampons during menses is unrelated to tetracycline use. The drug treats bacterial infections, not menstrual management, and has no gynecological implications requiring tampon use. This choice is irrelevant to the medication’s administration or side effect profile.