The use of diuretics in the treatment of heart failure may lead to what condition?
Fluid retention.
Hypotension.
Hyperglycemia.
Diarrhea.
The Correct Answer is B
Diuretics are medicines that help the kidneys get rid of excess water and salt, which can ease the symptoms of heart failure, such as breathlessness and swelling. However, diuretics may also lower the blood pressure by reducing the blood volume and the cardiac output. This can cause symptoms such as dizziness, fatigue, or fainting. Hypotension is defined as a systolic blood pressure lower than 90 mmHg or a diastolic blood pressure lower than 60 mmHg.
Choice A is wrong because fluid retention is the opposite of what diuretics do. Diuretics increase the urine output and decrease the fluid accumulation in the body.
Choice C is wrong because hyperglycemia is not a common side effect of diuretics. Hyperglycemia is a condition where the blood sugar level is too high. Diuretics may affect the blood sugar level in some cases, but usually not significantly.
Choice D is wrong because diarrhea is not a typical side effect of diuretics.
Diarrhea is a condition where the stool is loose and watery. Diuretics may cause some gastrointestinal discomfort, such as nausea or cramps, but not diarrhea.
Normal ranges for blood pressure are 120/80 mmHg for systolic/diastolic in healthy adults, and 140/90 mmHg or higher for hypertension. Normal ranges for blood sugar are 70-100 mg/dL for fasting glucose, and less than 140 mg/dL for postprandial glucose.
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Related Questions
Correct Answer is D
Explanation
Angiotensin receptor blockers (ARBs) are a class of drugs that block the action of angiotensin II, a hormone that causes blood vessels to constrict and raise blood pressure. Examples of ARBs include losartan, valsartan, candesartan, and irbesartan.ARBs are used to treat hypertension, heart failure, and chronic kidney disease.
Choice A is wrong because calcium channel blockers (CCBs) are a class of drugs that prevent calcium from entering the cells of the heart and blood vessels, causing them to relax and lower blood pressure.
Examples of CCBs include amlodipine, diltiazem, verapamil, and nifedipine.CCBs are used to treat hypertension, angina, and arrhythmias.
Choice B is wrong because beta blockers are a class of drugs that reduce the heart rate and force of contraction, lowering the cardiac output and blood pressure.
Examples of beta blockers include atenolol, metoprolol, propranolol, and bisoprolol.Beta blockers are used to treat hypertension, angina, heart failure, and arrhythmias.
Choice C is wrong because platelet inhibitors are a class of drugs that prevent platelets from clumping together and forming blood clots.
Examples of platelet inhibitors include aspirin, clopidogrel, ticagrelor, and prasugrel.Platelet inhibitors are used to prevent or treat cardiovascular events such as heart attack or stroke.
Choice E is wrong because ACE inhibitors are a class of drugs that inhibit the enzyme that converts angiotensin I to angiotensin II, reducing the production of this vasoconstrictor hormone.
Examples of ACE inhibitors include lisinopril, enalapril, ramipril, and captopril.ACE inhibitors are used to treat hypertension, heart failure, and chronic kidney disease.
Correct Answer is B
Explanation
Diuretics are drugs that increase the amount of urine and salt (sodium) excreted by the kidneys. They are used to treat high blood pressure, heart failure, and edema (fluid retention). However, some diuretics can cause low levels of potassium in the blood (hypokalemia), which can lead to muscle weakness, cramps, and arrhythmias. To prevent this, a combination of diuretics acting on different parts of the kidney (such as a loop diuretic and a thiazide diuretic) may be prescribed.This way, the potassium-sparing effect of one diuretic can balance the potassium-wasting effect of the other, while still achieving a net sodium loss.
Choice A is wrong because they are not a part of the initial diuretic therapy.Combination diuretic therapy is usually reserved for patients who are resistant to or intolerant of monotherapy.
Choice C is wrong because little follow up is not needed after the initial treatment.Patients on combination diuretic therapy require close monitoring of their blood pressure, electrolytes, renal function, and weight to avoid adverse effects such as dehydration, hyponatremia, hypotension, and worsening renal function.
Choice D is wrong because they do not increase the risk of hypokalemia.As explained above, combination diuretic therapy aims to reduce the risk of hypokalemia by using a potassium-sparing diuretic along with a potassium-wasting diuretic.
Normal ranges for serum potassium are 3.5 to 5.0 mmol/L and for serum sodium are 135 to 145 mmol/L.
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