Choose the group that is correct.
Select all that apply.

Alpha 1 adrenergic blocking agents have a vasodilating effect and can be used for the management of hypertension. They work by blocking the alpha 1 receptors on the vascular smooth muscle, which normally cause vasoconstriction when stimulated by catecholamines like epinephrine and norepinephrine.By preventing this constriction, alpha 1 blockers lower the peripheral resistance and blood pressure

Choice A is wrong because alpha 3 adrenergic blockers do not exist.There are only two types of alpha receptors: alpha 1 and alpha 2

Choice B is wrong because alpha 2 adrenergic antagonists do not have a vasodilating effect.

They block the alpha 2 receptors, which are located presynaptically on the sympathetic nerve terminals and postsynaptically on some vascular smooth muscle cells.Alpha 2 receptors inhibit the release of norepinephrine when activated, so blocking them would increase the sympathetic activity and vasoconstriction

Choice C is wrong because alpha 1 adrenergic agonists do not have a vasodilating effect.

They stimulate the alpha 1 receptors, which cause vasoconstriction and increase the blood pressure.Alpha 1 agonists are used to treat hypotension and nasal congestion

Anticoagulants are medicines that increase the time it takes for blood to clot.They do not dissolve existing clots, but they can stop them from getting bigger or prevent new clots from forming.Anticoagulants work by interfering with different steps of the blood coagulation pathway, which is a complex process that involves many clotting factors.

Choice A is wrong because anticoagulants do not dissolve existing clots.To dissolve clots, you need medicines called thrombolytics or fibrinolytics, which break down the fibrin that holds the clots together.

Choice B is wrong because anticoagulants do not transport platelets.

Platelets are blood cells that help with clotting by sticking together and forming a plug at the site of an injury.Anticoagulants may affect the function of platelets, but they do not move them around.

Choice D is wrong because anticoagulants do not increase blood viscosity.

Viscosity is a measure of how thick and sticky a fluid is.

Anticoagulants are sometimes called blood thinners, but they do not actually change the viscosity of blood.They just make it less likely to clot.

Normal ranges for blood clotting tests vary depending on the type of test and the laboratory that performs it.

Some common tests and their normal ranges are:

• Prothrombin time (PT): 11 to 13.5 seconds

• International normalized ratio (INR): 0.8 to 1.2

• Activated partial thromboplastin time (aPTT): 25 to 35 seconds

• Anti-factor Xa: 0.3 to 0.7 units/mL

• D-dimer: less than 0.5 mcg/mL