What cardiac pathologic condition contributes to ventricular remodeling?
Myocardial ischemia
Right ventricular failure
Left ventricular hypertrophy
Contractile dysfunction
The Correct Answer is A
A. Myocardial ischemia: Myocardial ischemia contributes to ventricular remodeling by causing damage to the heart muscle, leading to changes in the size, shape, and function of the ventricles. The process involves cellular and molecular alterations in response to ischemic injury, ultimately resulting in adverse remodeling that can exacerbate heart failure.
B. Right ventricular failure: Right ventricular failure may occur as a consequence of other cardiac conditions but is not a direct contributor to ventricular remodeling. Instead, it is often a result of left-sided heart failure or pulmonary hypertension, making it secondary to the primary pathologic changes.
C. Left ventricular hypertrophy: Left ventricular hypertrophy can occur as a response to chronic pressure overload (such as hypertension) but is a result of ventricular remodeling rather than a direct contributor to the remodeling process itself. It may indicate underlying issues rather than cause them.
D. Contractile dysfunction: Contractile dysfunction reflects impaired heart muscle contraction but does not directly cause ventricular remodeling. While it can be a consequence of remodeling due to conditions like ischemia or heart failure, it does not initiate the remodeling process itself.
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Related Questions
Correct Answer is C
Explanation
A. Prolonged PR interval: A prolonged PR interval is typically indicative of first-degree atrioventricular (AV) block and does not specifically relate to the presence of myocardial infarction (MI) that extends through the myocardium.
B. ST depression: ST depression can indicate subendocardial ischemia, but it is not a definitive change associated with a full-thickness myocardial infarction. It is more commonly seen during stress testing or in cases of angina rather than a transmural infarction.
C. ST elevation: ST elevation is a characteristic finding in cases of transmural myocardial infarction (MI), indicating that the injury extends through the myocardium from the endocardium to the epicardium. This elevation occurs due to the acute injury to the myocardial cells, leading to changes in the electrical activity as reflected on the ECG.
D. Prolonged QT interval: A prolonged QT interval is associated with an increased risk of arrhythmias but does not specifically indicate a myocardial infarction that penetrates through the myocardium. It is generally not directly related to the ischemic process of an MI.
Correct Answer is A
Explanation
A. Hospital-acquired pneumonia: Pneumonia that develops 48 hours or more after hospital admission is classified as hospital-acquired pneumonia (HAP). It is caused by pathogens acquired in the hospital setting, often involving multidrug-resistant organisms such as Pseudomonas aeruginosa, Staphylococcus aureus (including MRSA), and Klebsiella pneumoniae. Patients who are intubated, have prolonged hospital stays, or have weakened immune defenses are at higher risk.
B. Immunocompromised pneumonia: Pneumonia in immunocompromised patients occurs due to weakened host defenses, such as in individuals with HIV/AIDS, those undergoing chemotherapy, or transplant recipients on immunosuppressive therapy. While these patients can develop HAP, pneumonia due to opportunistic infections like Pneumocystis jirovecii or fungal infections is categorized separately.
C. Community-acquired pneumonia: Pneumonia acquired outside the hospital or within the first 48 hours of admission is classified as community-acquired pneumonia (CAP). Typical pathogens include Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae. CAP is usually less resistant to antibiotics compared to HAP.
D. Viral pneumonia: Pneumonia caused by viral pathogens such as influenza, respiratory syncytial virus (RSV), or SARS-CoV-2 is classified based on the causative agent rather than the setting in which it was acquired. Although viruses can cause both CAP and HAP, the classification of pneumonia is determined by the timing of onset and exposure risks.
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