What role do the kidneys have in the pharmacokinetics process?

Excretion

Absorption

Metabolism

Distribution

Answer and Explanation

The Correct Answer is A

A) Excretion:
This is the correct answer. The kidneys play a crucial role in the excretion of drugs and their metabolites from the body. After drugs undergo metabolism in the liver or other tissues, the resulting metabolites are often water-soluble and can be filtered by the kidneys into the urine. This process helps eliminate drugs and their byproducts from the body, preventing their accumulation and potential toxicity.

B) Absorption:
Absorption refers to the movement of drugs from the site of administration into the bloodstream. While the kidneys do not directly facilitate drug absorption, they may indirectly influence drug absorption by regulating blood flow and systemic circulation.

C) Metabolism:
Metabolism, or biotransformation, involves the enzymatic alteration of drugs into metabolites, which are often more water-soluble and easier to excrete. While the liver is the primary site of drug metabolism, the kidneys do not play a direct role in drug metabolism.

D) Distribution:
Distribution refers to the movement of drugs from the bloodstream to various tissues and organs in the body. While the kidneys do not directly influence drug distribution, changes in renal function can affect drug distribution by altering blood flow and plasma protein binding. However, the primary role of the kidneys in pharmacokinetics is excretion, not distribution.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is ["125"]

Explanation

Here's the breakdown of the calculation:

Total volume of fluid to infuse (mL): 1000 mL

Infusion time (hours): 8 hours

Flow rate (mL/hr) = Total volume (mL) / Infusion time (hours)

Flow rate (mL/hr) = 1000 mL / 8 hours = 125 mL/hr (round to nearest whole number as requested)

Therefore, the nurse should program the pump to deliver 125 mL/hr.

A. "I will weigh myself daily and report significant changes in weight." B. "If my leg gets swollen again, I'll be sure to take an additional pill." C. "I will take my medication before bedtime." D. "I will have to limit my high sugar foods."

Correct Answer is A

Explanation

A) "I will weigh myself daily and report significant changes in weight":
This statement demonstrates an understanding of the nurse's teaching about diuretics. Diuretics are medications that promote diuresis, leading to increased urine output and fluid loss. Monitoring weight daily can help the client identify fluid retention or volume overload, which are common concerns in individuals taking diuretics. Significant changes in weight, such as sudden increases, may indicate fluid retention or worsening heart failure and should be reported to the healthcare provider promptly for further evaluation.

B) "If my leg gets swollen again, I'll be sure to take an additional pill":
This statement indicates a misunderstanding of the nurse's teaching. Taking an additional pill without healthcare provider guidance can lead to medication overdose and potential adverse effects. It's important for clients to follow the prescribed dosage regimen and consult their healthcare provider before making any changes to their medication regimen.

C) "I will take my medication before bedtime":
While taking diuretics before bedtime may be appropriate for some individuals, it is not a universal recommendation. The timing of diuretic administration can vary depending on the specific type of diuretic prescribed, the client's individual needs, and the presence of any coexisting conditions. Therefore, this statement does not necessarily indicate an understanding of the nurse's teaching about diuretics.

D) "I will have to limit my high sugar foods":
This statement does not directly relate to the nurse's teaching about diuretics. While dietary modifications may be necessary for certain health conditions, such as diabetes, they are not specifically related to the mechanism of action or management of diuretic therapy. Therefore, this statement does not demonstrate an understanding of the nurse's teaching about diuretics.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

What role do the kidneys have in the pharmacokinetics process?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is preparing to administer 0.45% sodium chloride (NaCl) 1000 mL IV to infuse over 8 hr. The nurse should set the IV pump to deliver how many mL/hr? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero) _mL/hr

Correct Answer is ["125"]

Explanation

What statement by the client indicates that the client understands the nurse's teaching about diuretics?

Correct Answer is A

Explanation

A 27-year-old male is taking an anticholinergic drug as adjunctive therapy to treat his peptic ulcer disease. The client comes to the clinic and tells the nurse that he "feels his heart beating." What adverse effect is the client experiencing from the anticholinergic medication?

ACE inhibitors work on the RAAS to prevent the conversion of angiotensin I to angiotensin II. Because this blocking occurs in the cells in the lung, which is usually the site of this conversion, the use of ACE inhibitors often results in

A client taking anticholinergic drugs should be taught to minimize the risks of heat exhaustion and heat stroke. What would be one way to meet this goal?

A nurse is preparing to administer vancomycin 15 mg/kg/day divided equally every 12 hr. The client weighs 198 lb. How many mg should the nurse administer with each dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

What assessment should the nurse make before administering beta-adrenergic blocking agents?

A nurse caring for a client”who has hypertension and asks the nurse about a prescription for propranolol. The nurse should inform the client that this medication is contraindicated in clients who have a history of which of the following conditions?

The client has been ordered a nonselective beta-blocking agent called propranolol, PO. Propranolol is used in the treatment of which disorders (Select All that Apply.)