When evaluating a patient who is taking orlistat, which is an intended therapeutic effect?

Decreased weight

Increased appetite

Decreased hyperactivity

Increased wakefulness

Answer and Explanation

The Correct Answer is A

A.   Decreased weight: Orlistat is a medication used for weight management by inhibiting the absorption of dietary fats. Its intended therapeutic effect is to promote weight loss by reducing the amount of fat absorbed from the diet.
B.   Increased appetite: Orlistat does not increase appetite; rather, it may help control appetite by promoting satiety through its mechanism of action.
C.   Decreased hyperactivity: Orlistat is not indicated for the treatment of hyperactivity.

D. Increased wakefulness: Orlistat does not affect wakefulness; it primarily acts in the gastrointestinal tract to inhibit fat absorption.

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Correct Answer is B

Explanation

A. Egg salad sandwich: Eggs are generally considered safe to consume with MAOIs. There are no significant interactions between egg salad and MAOIs.
B. Pepperoni pizza: Pepperoni contains high levels of tyramine, which can cause a hypertensive crisis when consumed with MAOIs. Therefore, pepperoni pizza should be avoided by patients
taking MAOIs.

C. Pancakes and maple syrup: Pancakes and maple syrup are generally safe choices with MAOIs, as they do not contain high levels of tyramine.
D. Fried eggs over-easy: Like egg salad, fried eggs are generally considered safe to consume with MAOIs. There are no significant interactions between fried eggs and MAOIs.

A. Carbidopa prevents the breakdown of levodopa in the periphery. B. Carbidopa is the biologic precursor of dopamine and can penetrate into the central nervous system. C. Carbidopa allows for larger doses of levodopa to be given. D. There are concerns about drug-food interactions with levodopa therapy that do not exist with the combination therapy.

Correct Answer is A

Explanation

A. Carbidopa prevents the breakdown of levodopa in the periphery, specifically in the gastrointestinal tract and peripheral tissues, allowing more levodopa to reach the brain and be converted to dopamine. This enhances the effectiveness of levodopa therapy in managing the symptoms of Parkinson's disease.
B. Carbidopa is not the biologic precursor of dopamine. It is a peripheral decarboxylase inhibitor that does not cross the blood-brain barrier.
C. Carbidopa does not directly allow for larger doses of levodopa to be given. However, by

inhibiting the peripheral breakdown of levodopa, it enhances the availability of levodopa to the central nervous system, potentially improving therapeutic efficacy.
D. While levodopa-carbidopa combination therapy may have fewer drug-food interactions compared to levodopa alone, the primary reason for combining these medications is to enhance the effectiveness of levodopa by preventing its peripheral breakdown.

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When evaluating a patient who is taking orlistat, which is an intended therapeutic effect?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is reviewing the food choices of a patient who is taking a monoamine oxidase inhibitor (MAOI). Which food choice would indicate the need for additional teaching?

Correct Answer is B

Explanation

A patient has been given a prescription for levodopa-carbidopa for a new diagnosis of Parkinson's disease. The patient asks the nurse, "Why are there two drugs in this pill?" The nurse's best response reflects which fact?

Correct Answer is A

Explanation

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