Where do enteric coated tablets typically disintegrate in the body?
Esophagus
Duodenum
Stomach
Colon
The Correct Answer is B
A) Esophagus
Enteric-coated tablets are designed to not dissolve or disintegrate in the esophagus. They are coated with a protective layer that prevents the tablet from breaking down in the acidic environment of the stomach. This is to ensure that the medication is released in the part of the digestive tract where it is most needed, typically beyond the stomach.
B) Duodenum
Enteric-coated tablets are designed to disintegrate in the duodenum, which is the first part of the small intestine. The coating protects the tablet from stomach acid, allowing it to pass intact through the stomach and into the small intestine, where the pH is higher and the coating dissolves, releasing the medication for absorption.
C) Stomach
Enteric-coated tablets are specifically designed not to disintegrate in the stomach because the stomach's acidic environment could either damage the drug or cause premature release. The coating ensures that the drug is protected until it reaches the more neutral pH of the duodenum.
D) Colon
The colon is too far along in the digestive tract for enteric-coated tablets to typically disintegrate. The design of enteric coatings is intended to protect the drug until it reaches the duodenum, where absorption is most efficient. Enteric coatings are not meant to disintegrate in the colon.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["C","D","E","F"]
Explanation
A) Social Media:
Social media is not a reliable source for evaluating medication information. Although patients may share their experiences, the information on social media can be anecdotal, unverified, and often lacks scientific evidence. Medical professionals should avoid using social media as a reference for clinical decision-making and instead rely on trusted, evidence-based resources.
B) Wikipedia:
While Wikipedia may offer general overviews of various medications, it is a crowdsourced platform and not a peer-reviewed or professional resource. The information on Wikipedia can be edited by anyone, which raises concerns about accuracy and reliability. While useful for a quick overview, it is not recommended for in-depth medication information or clinical decision-making.
C) Physicians' Desk Reference (PDR):
The Physicians' Desk Reference (PDR) is a well-established, reliable resource for medication information. It includes detailed drug monographs, including indications, dosing, contraindications, adverse effects, and drug interactions. Although it is often considered more of a reference for healthcare providers, it is a trusted and authoritative source for accurate medication information.
D) Lexicomp:
Lexicomp is an evidence-based, reputable resource that provides comprehensive drug information, including dosage recommendations, side effects, interactions, and clinical guidelines. It is frequently used by healthcare providers for decision-making in clinical practice and is considered highly reliable.
E) Micromedex:
Micromedex is another reliable, evidence-based drug information database widely used in healthcare settings. It provides drug monographs, information on drug interactions, adverse effects, and clinical recommendations, making it an essential tool for clinical decision-making.
F) American Hospital Formulary Service (AHFS) Drug Information:
The American Hospital Formulary Service (AHFS) is a trusted source of drug information that is used by healthcare providers to obtain reliable, evidence-based data. It includes detailed monographs on prescription drugs, over-the-counter medications, and other therapeutic agents, which are useful for clinicians when assessing treatment options.
Correct Answer is C
Explanation
A) Yes. Antacids can help alleviate heartburn caused by digoxin.
While antacids can help relieve heartburn, they do not directly alleviate heartburn caused by digoxin. In fact, antacids can interact with digoxin in a way that affects its absorption, potentially leading to suboptimal therapeutic effects.
B) Yes, you can take antacids with digoxin without any interactions.
Antacids can interact with digoxin and reduce its absorption, particularly those that contain aluminum, magnesium, or calcium. Therefore, it is important to space the administration of these medications to avoid potential drug interactions.
C) Yes, but make sure to take the antacid at least 2 hours before or after taking digoxin.. Antacids, especially those containing aluminum, calcium, or magnesium, can decrease the absorption of digoxin, reducing its effectiveness. To prevent this interaction, the nurse should advise the client to take the antacid at least 2 hours before or after taking digoxin to ensure that digoxin is properly absorbed and remains effective.
D) No, antacids can decrease the absorption of digoxin and result in a decreased drug effect.
While this statement is partly true in that antacids can decrease digoxin absorption, it is too absolute to recommend avoiding antacids altogether. The key is proper timing—taking antacids at least 2 hours apart from digoxin.
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