Where do enteric coated tablets typically disintegrate in the body?
Esophagus
Duodenum
Stomach
Colon
The Correct Answer is B
A) Esophagus
Enteric-coated tablets are designed to not dissolve or disintegrate in the esophagus. They are coated with a protective layer that prevents the tablet from breaking down in the acidic environment of the stomach. This is to ensure that the medication is released in the part of the digestive tract where it is most needed, typically beyond the stomach.
B) Duodenum
Enteric-coated tablets are designed to disintegrate in the duodenum, which is the first part of the small intestine. The coating protects the tablet from stomach acid, allowing it to pass intact through the stomach and into the small intestine, where the pH is higher and the coating dissolves, releasing the medication for absorption.
C) Stomach
Enteric-coated tablets are specifically designed not to disintegrate in the stomach because the stomach's acidic environment could either damage the drug or cause premature release. The coating ensures that the drug is protected until it reaches the more neutral pH of the duodenum.
D) Colon
The colon is too far along in the digestive tract for enteric-coated tablets to typically disintegrate. The design of enteric coatings is intended to protect the drug until it reaches the duodenum, where absorption is most efficient. Enteric coatings are not meant to disintegrate in the colon.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A) "If I develop new symptoms like severe diarrhea, I should ignore them and finish the antibiotics."
New symptoms like severe diarrhea, especially if it is watery or bloody, can be a sign of a superinfection, such as Clostridium difficile (C. diff), which is associated with antibiotic use. It is essential for the client to report these symptoms to their healthcare provider immediately. Ignoring such symptoms can lead to serious complications.
B) "I need to finish all my antibiotics and report any unusual symptoms like a white coating on my tongue to my doctor."
Completing the full course of antibiotics is crucial to fully eradicate the infection and prevent the development of antibiotic resistance. The white coating on the tongue could indicate a fungal superinfection, such as oral thrush, which requires medical attention. This statement demonstrates an understanding of the importance of finishing antibiotics and recognizing potential side effects or superinfections.
C) "It is okay to share my antibiotics with family members if they have similar symptoms to mine."
Antibiotics should never be shared with others, even if they have similar symptoms. The antibiotics prescribed to a client are tailored to treat their specific infection, and taking the wrong antibiotic can lead to ineffective treatment, drug resistance, or adverse reactions. Sharing medication is dangerous and illegal.
D) "I should stop taking the antibiotics as soon as I feel better to avoid any side effects."
It is important to complete the full course of antibiotics as prescribed, even if the client starts feeling better before the course is finished. Stopping antibiotics prematurely can result in the infection not being fully treated, leading to a relapse or the development of antibiotic-resistant bacteria.
Correct Answer is D
Explanation
A) Distribution:. Distribution refers to the process by which a drug is transported throughout the body after it is absorbed into the bloodstream. It involves the movement of the drug to various tissues and organs, where it can exert its effects. Factors such as blood flow, tissue permeability, and protein binding affect distribution.
B) Metabolism:
Metabolism refers to the biochemical process by which the body breaks down drugs into metabolites, usually in the liver. Metabolism can transform drugs into more easily excreted forms and sometimes alters the drug’s activity. It is essential for drug clearance and can affect drug efficacy and toxicity.
C) Absorption:
Absorption is the first step in pharmacokinetics, where the drug enters the bloodstream after being administered. It occurs primarily in the gastrointestinal (GI) tract for oral medications but can also happen in other routes like subcutaneous or intramuscular injections. The rate and extent of absorption are influenced by factors such as drug formulation, route of administration, and presence of food.
D) Synthesis:
Synthesis refers to the process of creating substances, such as drugs or other compounds, typically within the body or in a laboratory setting. While drug synthesis is crucial in drug development, it is not a step involved in the movement or processing of drugs within the body (which is what pharmacokinetics describes). Pharmacokinetics focuses on how the body handles drugs, not how they are created.
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