Which condition is a cause of an acquired murmur?

A. Norepinephrine causes bronchial smooth muscle contraction and mucus secretion but it also causes high blood pressure: This statement is misleading in the context of asthma. Norepinephrine primarily acts on alpha and beta receptors, influencing blood pressure and bronchodilation but is not the main mediator in asthma pathophysiology. The focus should be on inflammation and airway responsiveness.

B. Uncontrolled inflammation leads to increased bronchial hyperresponsiveness and eventual scarring: This statement accurately describes the pathophysiologic process in asthma. Persistent inflammation in asthma can cause increased bronchial hyperresponsiveness, leading to airway narrowing and potential long-term remodeling and scarring of the airways if not controlled. Effective management is essential to prevent these adverse outcomes.

C. Immunoglobulin G causes smooth muscle contraction which will eventually weaken the respiratory muscles: Immunoglobulin E (IgE) is primarily involved in allergic reactions and asthma, and it does not directly cause smooth muscle contraction that weakens respiratory muscles.

D. The release of epinephrine leads to development of cardiac dysrhythmias: While epinephrine can have cardiovascular effects, including increased heart rate and potential for dysrhythmias, this is not directly relevant to the pathophysiology of asthma. The focus in asthma management is on controlling airway inflammation and bronchoconstriction rather than on cardiac issues.

A. Obstructive: Obstructive pulmonary disease is characterized by increased resistance in the airways, making it more difficult to expire air. Conditions such as asthma and chronic obstructive pulmonary disease (COPD) lead to airflow limitation, requiring greater force to expel air from the lungs.

B. Communicable: Communicable pulmonary diseases refer to infections that can be transmitted from person to person, such as tuberculosis or influenza. This classification does not directly relate to the mechanics of airflow and does not specifically require more force to expire air.

C. Acute: Acute pulmonary disease describes a sudden onset of symptoms, which can be caused by various conditions (e.g., pneumonia or pulmonary embolism). The term "acute" does not inherently indicate a need for increased expiratory force and can encompass both obstructive and restrictive patterns.

D. Restrictive: Restrictive pulmonary disease involves reduced lung volume and compliance, making it difficult to expand the lungs fully during inspiration. While patients may struggle to inhale adequately, they typically do not require increased force to expire air, as expiratory airflow is usually not obstructed in the same manner as in obstructive diseases.