Which of the following bones is often affected in Paget's disease?
Humerus (arm bone)
Radius (forearm bone)
Femur (thigh bone)
Fibula (lower leg bone)
The Correct Answer is C
The femur, which is the thigh bone, is often affected in Paget's disease. The condition commonly involves the axial skeleton, such as the skull, spine, and pelvis, as well as the long bones like the femur.
a. Humerus (arm bone): The humerus can be affected in Paget's disease, but it is not as commonly involved as the femur.
b. Radius (forearm bone): The radius can be affected in Paget's disease, but it is not as commonly involved as the femur.
d. Fibula (lower leg bone): The fibula can be affected in Paget's disease, but it is not as commonly involved as the femur.
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Related Questions
Correct Answer is B
Explanation
Paget's disease is a bone disorder that causes abnormal bone remodeling, leading to enlarged, weak, and deformed bones.
a. Muscles: Paget's disease primarily affects bones, not muscles. While muscles surrounding affected bones may be impacted indirectly, they are not the primary target of the disease.
c. Skin: Paget's disease does not affect the skin. It is a bone disorder and does not involve the skin.
d. Lungs: Paget's disease does not directly affect the lungs. The disease primarily involves bone remodeling, not lung function.
Correct Answer is D
Explanation
Bone pain is a common clinical manifestation of Paget's disease, but another hallmark of the condition is the development of bone deformities. The abnormal bone remodeling in Paget's disease can lead to enlarged, misshapen bones, particularly in weight-bearing areas such as the skull, pelvis, and long bones.
a. Muscle weakness: While bone pain can lead to discomfort and reduced mobility, muscle weakness is not a specific clinical manifestation of Paget's disease.
b. Hypercalcemia: Hypercalcemia (elevated blood calcium levels) is not typically associated with Paget's disease. Instead, the condition is characterized by disorganized bone remodeling.
c. Joint swelling: Joint swelling is not a primary clinical manifestation of Paget's disease. Bone deformities are more characteristic of the condition.
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