Paget's disease can lead to an increased risk of which complication?
Heart attack
Stroke
Osteoporosis
Bone fractures
The Correct Answer is D
Paget's disease can weaken bones, leading to an increased risk of bone fractures. The abnormal bone remodeling and increased bone turnover can result in bones that are more susceptible to breaking.
a. Heart attack: Paget's disease primarily affects bones, not the cardiovascular system. There is no direct association between Paget's disease and an increased risk of heart attacks.
b. Stroke: Paget's disease does not increase the risk of stroke. Stroke is a condition primarily related to the brain and blood vessels, not bones.
c. Osteoporosis: While both Paget's disease and osteoporosis involve changes in bone density, they are distinct conditions. Paget's disease leads to enlarged and weakened bones, while osteoporosis leads to decreased bone density and increased fracture risk.
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Related Questions
Correct Answer is C
Explanation
Bisphosphonates are commonly used as the first-line treatment for Paget's disease. They work by slowing down bone resorption and promoting more balanced bone remodeling, helping to control the excessive bone turnover characteristic of the condition.
a. Calcium supplements: While calcium supplements are essential for overall bone health, they are not the first-line treatment for Paget's disease. Bisphosphonates specifically target the abnormal bone remodeling associated with the condition.
b. Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs may help manage pain and inflammation associated with Paget's disease, but they do not directly address the underlying bone remodeling abnormalities. Bisphosphonates are more effective in treating the condition.
d. Vitamin D supplements: Vitamin D is necessary for calcium absorption and bone health, but it is not the primary treatment for Paget's disease. Bisphosphonates are the mainstay of therapy.
Correct Answer is C
Explanation
The increased bone turnover and remodeling in Paget's disease can cause warmth and erythema (redness) over the affected bones. This is due to the increased blood flow and metabolic activity in the affected areas.
a. Cool, clammy skin: Cool, clammy skin is not directly related to the increased bone turnover and remodeling in Paget's disease. It may be related to other factors, such as circulation or environmental conditions.
b. Pulsating chest pain: Pulsating chest pain is not a typical finding in Paget's disease. It may be related to other cardiac or respiratory conditions.
d. Enlarged skull circumference: An enlarged skull circumference is a common manifestation of Paget's disease, but it is not directly related to the increased bone turnover and remodeling. It results from excessive bone growth in the skull bones.
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